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Figure 2 | Lipids in Health and Disease

Figure 2

From: The activation of CD14, TLR4, and TLR2 by mmLDL induces IL-1β, IL-6, and IL-10 secretion in human monocytes and macrophages

Figure 2

Role of CD14 and TLR4 in secretion of IL-6 in response to mmLDL. Human monocytes (2A) and macrophages (2B) were treated with anti-CD14, anti-TLR4, or both antibodies (10 μg/ml) for 1 hour before incubation with mmLDL (50 μg/ml and 70 μg/ml, respectively). Monocytes and macrophages were incubated with irrelevant antibody (10 μg/ml) in the presence or absence of mmLDL (50 μg/ml and 70 μg/ml, respectively). The concentration of IL-6 in culture supernatants was determined by CBA. *p < 0.005.

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Lipids in Health and Disease

ISSN: 1476-511X