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Figure 3 | Lipids in Health and Disease

Figure 3

From: The activation of CD14, TLR4, and TLR2 by mmLDL induces IL-1β, IL-6, and IL-10 secretion in human monocytes and macrophages

Figure 3

Role of TLR2 in secretion of IL-1β and IL-6 in response to mmLDL. Human monocytes and macrophages were treated with anti-TLR2 (10 μg/ml) for 1 hour before stimulation with mmLDL (50 μg/ml and 70 μg/ml, respectively). Monocytes and macrophages were incubated with irrelevant antibody (10 μg/ml) in the presence or absence of mmLDL (50 μg/ml and 70 μg/ml, respectively). The concentrations of IL-1β and IL-6 in culture supernatants of monocytes (3A and 3B) and macrophages (3C and 3D) were determined by CBA, respectively. *p < 0.005.

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