Association of plasma lipids ratios and distribution of HDL subclasses. This chart was constructed from data in references [8, 11, 12]. With the elevation of TG/HDL-C, TC/HDL-C, and LDL-C/HDL-C ratios, the contents of small-sized preβ1-HDL increased progressively, but those of large-sized HDL2b decreased progressively. Moreover, the characteristic of HDL subclass distribution for subjects with TG/HDL-C, TC/HDL-C, and LDL-C/HDL-C was 1.5, 3.0, and 1.7, respectively in accordance with that for the normolipidemic subject in our previous study. Especially, the subjects with LDL-C/HDL-C > 5.6 group had significant higher preβ1-HDL and significant lower HDL2b, which resulted in the ratio of HDL2b/preβ1-HDL from 4.8 in LDL-C/HDL-C < 1.7 group decreased to 1.4.