Skip to main content
Figure 4 | Lipids in Health and Disease

Figure 4

From: Docosahexaenoic acid prevents dendritic cell maturation and in vitro and in vivo expression of the IL-12 cytokine family

Figure 4

Effects of DHA on IL-12p70 production initiated by signaling through various TLRs. CD11c+ DC (1 × 106 cells/ml for IL-12p70 and 2 × 106 cells/ml for IL-23) were pretreated with 25 μM DHA for 24 h followed by different TLR ligands (LPS 0.1 μg/ml, PGN 10 μg/ml, CpG 1 μM, poly I:C 50 μg/ml, CpG 1 μM + poly I:C 50 μg/ml) for an additional 12 h (for IL-23) or 24 h (for IL-12p70). Supernatants were harvested and assayed for IL-12p70 or IL-23 by ELISA.

Back to article page

Lipids in Health and Disease

ISSN: 1476-511X