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Table 3 Serum ALT and AST levels in rats at the end of 12 week treatment

From: The effect of combination therapy of allicin and fenofibrate on high fat diet-induced vascular endothelium dysfunction and liver damage in rats

Groups

n

ALT(U/L)

AST(U/L)

Normal control

11

35.364 ± 2.730

81.546 ± 5.087

Model control

9

70.333 ± 3.500 a

134.778 ± 4.790 a

Fenofibrate

10

49.200 ± 4.022 ac

102.100 ± 5.840 ac

Allicin

10

41.500 ± 3.375 acd

92.100 ± 5.763 acd

Combination

10

42.100 ± 3.665 acd

90.400 ± 8.343bcd

  1. ALT: alanine transferase; AST: aspartate transferase; Values are means ± SD; a and b: Compared to Normal control, aP < 0.01,bP < 0.05; c: Compared to Model control, P < 0.01; d: Compared to Fenofibrate, P < 0.01