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Table 2 Plasma parameters in 3 month-old WNIN/Ob lean and obese rats.

From: A novel genetically-obese rat model with elevated 11beta-hydroxysteroid dehydrogenase type 1 activity in subcutaneous adipose tissue

 

Lean (n = 6)

Obese (n = 6)

Corticosterone (ng/ml)

213 ± 34

433 ± 50*

Insulin (μU/ml)

7.0 ± 3.6

206 ± 23*

Triglycerides (mg/dl)

46.5 ± 3.0

212 ± 29*

Glucose (mg/dl)

80.0 ± 2.0

86.0 ± 4.7

HOMA-IR

1.4 ± 0.8

52.5 ± 7.0*

Glucose AUC (mmol/l)

304 ± 13

472 ± 31*

Insulin AUC (μU/ml)

5.1 ± 1.2

32 ± 2.8*

Glucose AUC/Insulin AUC (× 1000)

74 ± 14

15 ± 1.4*

Leptin (ng/ml)

1.0 ± 0.1

14.2 ± 1.8*

TNF-α (pg/ml)

3.0 ± 1.6

Nd

IL-6 (ng/ml)

191 ± 62

57.5 ± 35

MCP-1 (μg/ml)

0.3 ± 0.1

2.5 ± 2.3

  1. Values are mean± S.E of 6 rats. Values with * mark are significant at P < 0.05 level (by student's t test). Comparisons were made between lean and obese phenotypes. Nd, non-detectable.
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