Table 1 Baseline and study end median values of Apolipoprotein B and cholesterol content in lipoprotein subclasses in the overall population and triglyceride subgroups in high risk patients
From: Are post-treatment low-density lipoprotein subclass pattern analyses potentially misleading?
(mg/dL) | Overall Population | Baseline Triglycerides <150 mg/dL | Baseline Triglycerides ≥150 mg/dL | |||
|---|---|---|---|---|---|---|
Baseline concentration | A40 + EZ n = 225 | A80 n = 222 | A40 + EZ n = 136 | A80 n = 140 | A40 + EZ n = 89 | A80 n = 82 |
Triglyceride | 131.0 | 135.5 | 109.0 | 107.5 | 195.8 | 191.0 |
Apo B* | 101.1 | 102.0 | 94.8 | 94.8 | 111.7 | 113.7 |
Total LDL-C* | 88.6 | 89.7 | 88.3 | 85.8 | 88.9 | 96.1 |
LDL1-C | 14.0 | 14.0 | 14.0 | 13.0 | 15.0 | 16.0 |
LDL2-C | 17.0 | 16.5 | 21.0 | 18.5 | 10.0 | 13.5 |
LDL3-C | 38.0 | 41.5 | 36.0 | 39.0 | 42.0 | 44.0 |
LDL4-C | 9.0 | 9.0 | 7.0 | 8.0 | 14.0 | 13.0 |
Non-HDL-C* | 117.4 | 118.0 | 109.3 | 107.3 | 130.9 | 135.5 |
HDL2-C | 9.0 | 10.0 | 10.0 | 10.00 | 8.0 | 8.5 |
HDL3-C | 36.0 | 36.0 | 38.0 | 36.0 | 33.0 | 34.0 |
Study end concentration | ||||||
Triglyceride | 117.0 | 124.0 | 92.0 | 104.0 | 166.5 | 170.0 |
Apo B* | 82.5 | 93.2 | 79.3 | 87.9 | 87.7 | 101.8 |
Total LDL-C* | 64.1 | 79.1 | 65.3 | 76.8 | 62.2 | 82.8 |
LDL1-C | 10.0 | 12.0 | 9.0 | 12.0 | 11.0 | 13.5 |
LDL2-C | 13.0 | 15.0 | 15.0 | 17.0 | 10.0 | 13.0 |
LDL3-C | 29.0 | 37.0 | 27.0 | 35.0 | 30.0 | 40.0 |
LDL4-C | 8.0 | 9.0 | 7.0 | 8.0 | 10.0 | 11.0 |
Non-HDL-C* | 89.5 | 106.4 | 84.8 | 99.0 | 97.5 | 118.6 |
HDL2-C | 10.0 | 9.5 | 10.0 | 10.0 | 9.0 | 8.0 |
HDL3-C | 35.0 | 35.0 | 37.0 | 36.0 | 33.0 | 34.0 |