Skip to main content

Advertisement

Table 3 Comparison of areas under the ROC curves (95% CI) for potential markers of insulin resistance (HOMA-IR§ > 2.5) of subjects categorized by body mass index

From: Low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio is the best surrogate marker for insulin resistance in non-obese Japanese adults

  AUC (95% CI)  
  Total Non-obese Overweight  
Body mass index Characteristics All N = 1,393 P -value <25.0 kg/m2 N = 1,042 P -value >25.0 kg/m2 N = 351 P -value
Triglycerides (mg/dL) 0.69 (0.45-0.73) <0.001 0.66 (0.59-0.72) <0.001 0.64 (0.58-0.71) <0.001
HDL cholesterol (mg/dL) 0.33 (0.28-0.37) <0.001 0.31 (0.24-0.38) <0.001 0.41 (0.35-0.48) 0.009
LDL cholesterol (mg/dL) 0.61 (0.56-0.65) <0.001 0.65 (0.58-0.72) <0.001 0.54 (0.48-0.61) 0.188
Triglycerides/HDL cholesterol ratio 0.70 (0.66-0.75) <0.001 0.69 (0.62-0.75) <0.001 0.64 (0.57-0.70) <0.001
Non-HDL cholesterol (mg/dL) 0.66 (0.61-0.70) <0.001 0.69 (0.62-0.75) <0.001 0.59 (0.52-0.65) 0.011
LDL-cholesterol/HDL-cholesterol ratio 0.69 (0.65-0.73) <0.001 0.74 (0.66-0.80) <0.001 0.58 (0.51-0.65) 0.021
  1. ROC, receiver operating characteristics; HOMA-IR, homeostasis of minimal assessment of insulin resistance; CI, confidence interval; AUC, area under ROC curve; HDL, high-density lipoprotein; LDL, low-density lipoprotein. §HOMA-IR was calculated using the following formula; {fasting blood glucose (mg/dL) X immuno-reactive insulin (mU/mL)}/405.