Polymorphism of rs1044925 in the acyl-CoA:cholesterol acyltransferase-1 gene and serum lipid levels in the Guangxi Bai Ku Yao and Han populations

Wu, Dong-Feng; Yin, Rui-Xing; Aung, Lynn Htet Htet; Hu, Xi-Jiang; Cao, Xiao-Li; Miao, Lin; Li, Qing; Yan, Ting-Ting; Wu, Jin-Zhen; Pan, Shang-Ling

doi:10.1186/1476-511X-9-139

Lipids in Health and Disease

Table 4 Correlative factors for serum lipid parameters between Bai Ku Yao and Han Chinese

From: Polymorphism of rs1044925 in the acyl-CoA:cholesterol acyltransferase-1 gene and serum lipid levels in the Guangxi Bai Ku Yao and Han populations

Lipid parameter	Relative factor	Unstandardized coefficient	Std. error	Standardized coefficient	t	P
Bai plus Han
TC	Body mass index	0.070	0.009	0.204	7.493	0.000
	Ethnic group	0.363	0.051	0.188	7.148	0.000
	Age	0.010	0.002	0.160	5.953	0.000
	Diastolic blood pressure	0.010	0.003	0.109	3.940	0.000
TG	Body mass index	0.070	0.012	0.165	5.742	0.000
	Alcohol consumption	0.185	0.074	0.076	2.478	0.013
	Sex	-0.247	0.074	-0.103	-3.355	0.001
	Diastolic blood pressure	0.008	0.003	0.066	2.286	0.022
HDL-C	Age	0.005	0.001	0.168	6.163	0.000
	Alcohol consumption	0.207	0.028	0.219	7.358	0.000
	Sex	0.127	0.028	0.135	4.566	0.000
	Body mass index	-0.015	0.005	-0.092	-3.334	0.001
	Diastolic blood pressure	0.003	0.001	0.057	2.024	0.043
	Ethnic group	0.247	0.025	0.264	9.979	0.000
LDL-C	Body mass index	0.059	0.007	0.224	8.004	0.000
	Age	0.007	0.001	0.143	5.136	0.000
	Alcohol consumption	-0.177	0.042	-0.117	-4.250	0.000
	Diastolic blood pressure	0.005	0.002	0.063	2.187	0.029
ApoAI	Age	0.004	0.001	0.194	7.110	0.000
	Alcohol consumption	0.143	0.018	0.233	7.849	0.000
	Ethnic group	0.120	0.016	0.198	7.479	0.000
	Diastolic blood pressure	0.002	0.001	0.069	2.519	0.012
	Sex	-0.037	0.018	-0.061	-2.068	0.039
ApoB	Body mass index	0.018	0.002	0.223	8.019	0.000
	Age	0.002	0.000	0.141	5.120	0.000
	Diastolic blood pressure	0.002	0.001	0.100	3.487	0.001
	Sex	0.032	0.012	0.071	2.613	0.009
	Ethnic group	0.034	0.012	0.076	2.852	0.004
ApoAI/ApoB	Alcohol consumption	0.227	0.037	0.172	6.219	0.000
	Body mass index	-0.034	0.006	-0.148	-5.360	0.000
Bai Ku Yao
TC	Body mass index	0.087	0.014	0.239	6.190	0.000
	Age	0.008	0.002	0.138	3.570	0.000
TG	Alcohol consumption	0.218	0.065	0.155	3.366	0.001
	Body mass index	0.055	0.016	0.137	3.486	0.001
	Sex	-0.229	0.089	-0.119	-2.581	0.010
HDL-C	Alcohol consumption	0.117	0.023	0.198	5.099	0.000
	Age	0.004	0.001	0.152	3.905	0.000
LDL-C	Body mass index	0.077	0.012	0.255	6.587	0.000
	Age	0.006	0.002	0.124	3.215	0.001
	Alcohol consumption	-0.093	0.041	-0.089	-2.278	0.023
ApoAI	Alcohol consumption	0.140	0.018	0.300	7.951	0.000
	Age	0.003	0.001	0.151	3.999	0.000
ApoB	Body mass index	0.023	0.004	0.249	6.458	0.000
	Age	0.002	0.001	0.117	3.036	0.002
ApoAI/ApoB	Alcohol consumption	0.278	0.040	0.266	6.916	0.000
	Body mass index	-0.048	0.012	-0.159	-4.127	0.000
Han Chinese
TC	Age	0.013	0.002	0.193	5.015	0.000
	Body mass index	0.055	0.012	0.173	4.410	0.000
	Diastolic blood pressure	0.017	0.004	0.173	4.285	0.000
	Sex	0.161	0.077	0.079	2.098	0.036
TG	Body mass index	0.071	0.018	0.164	4.005	0.000
	Alcohol consumption	0.309	0.090	0.135	3.448	0.001
	Diastolic blood pressure	0.011	0.005	0.084	2.033	0.042
HDL-C	Age	0.006	0.001	0.198	5.022	0.000
	Alcohol consumption	0.170	0.033	0.209	5.129	0.000
	Sex	0.212	0.040	0.213	5.258	0.000
	Body mass index	-0.020	0.006	-0.126	-3.172	0.002
	Diastolic blood pressure	0.005	0.002	0.099	2.429	0.015
LDL-C	Body mass index	0.053	0.009	0.221	5.726	0.000
	Age	0.009	0.002	0.190	4.858	0.000
	Alcohol consumption	-0.135	0.049	-0.107	-2.760	0.006
ApoAI	Age	0.004	0.001	0.251	6.467	0.000
	Alcohol consumption	0.086	0.018	0.189	4.721	0.000
	Sex	0.106	0.022	0.191	4.818	0.000
	Diastolic blood pressure	0.003	0.001	0.103	2.677	0.008
ApoB	Body mass index	0.015	0.003	0.218	5.547	0.000
	Age	0.003	0.001	0.195	5.069	0.000
	Diastolic blood pressure	0.003	0.001	0.119	2.979	0.003
ApoAI/ApoB	Body mass index	-0.027	0.007	-0.152	-3.847	0.000

TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoAI, apolipoprotein AI; ApoB, apolipoprotein B

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ISSN: 1476-511X

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