Blood lipids, homocysteine, stress factors, and vitamins in clinically stable multiple sclerosis patients

Table 1 Comparison of Blood Lipids, total Homocysteine, Uric Acid and Vitamins concentration in subjects with a Multiple Sclerosis and in healthy controls.

Molecule^a	Patients	Controls	P°
Vitamin B12	666.42 ± 354.16	493.70 ± 229.16	0.058
Folic acid	7.3 (2.8, 25.0)	5.9 (1.2, 16.0)	0.196
Uric acid	4.3 (2.8, 5.9)	4.1 (2.1, 7.3)	1.000
Homocysteine	9.3 (4.0, 86.5)	6.3 (3.2, 15.0)	0.032
Vitamin A	0.3 (0.1, 0.7)	0.4 (0.1, 2.4)	0.149
Vitamin E	12.0 (5.4, 26.5)	22.5 (1.9, 70.2)	0.001
Cholesterol	187.70 ± 40.30	169.07 ± 35.18	0.071
HDL-cholesterol	61.42 ± 14.85	50.05 ± 10.81	0.001
Triglyceride	92.82 ± 46.72	82.35 ± 44.52	0.401
E/CHL	0.07 ± 0.04	0.15 ± 0.08	0.001

*Vitamin B12 (pg/ml), total Cholesterol (mg%), HDL-cholesterol (mg%) and Triglyceride (mg %) had a normal distribution; mean values and standard deviation are reported. Folic acid (ng/ml), Uric acid (mg %), total Homocysteine (μmol/L), vitamin A (mgr/L), and vitamin E (mgr/L) had not a normal distribution; median values, minimum and maximum are reported.
° Student "t test" was used to calculate statistical significativity for vitamin B12, cholesterol, HDL-cholesterol, triglycerid, and E/CHL ratio. Mann-Whitney U test was used to calculate statistical significativity for folic acid, uric acid, homocysteine, vitamin A, and vitamin E.

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