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Table 2 Histological observations of hepatic tissue

From: Comparative antilipidemic effect of N-acetylcysteine and sesame oil administration in diet-induced hypercholesterolemic mice

Groups Steatosis Ballooning Portal inflammation Lobular activity Overall
NC 0.00 ± 0.00b,d 0.00 ± 0.00b,d 0.00 ± 0.00b,c,d 0.00 ± 0.00b,d 0.00 ± 0.00b,c,d
HC 2.00 ± 0.31a,c,d 1.40 ± 0.40a,c,d 1.80 ± 0.58a 1.20 ± 0.20a,c 6.40 ± 0.87a,c,d
HCN 0.28 ± 0.18b,d 0.28 ± 0.18b,d 1.28 ± 0.47a 0.28 ± 0.18b,d 2.14 ± 0.59a,b,d
HCS 3.00 ± 0.00a,b,c 2.12 ± 0.29a,c 2.00 ± 0.00a 1.87 ± 0.29a,c 9.00 ± 0.18a,b,c
  1. 3, severe; 2, moderate; 1, mild; 0, no changes in histology (scores)
  2. (NC), Control mice; (HC) mice fed high cholesterol diet; (HCN) mice fed the high cholesterol diet and treated with NAC; (HCS) fed the high cholesterol diet enriched with sesame oil.
  3. a: Significantly different from NC group
  4. b: Significantly different from HC group
  5. c: Significantly different from HCN group
  6. d: Significantly different from HCS group
  7. Values are presented as mean score ± standard error, P < 0.05.