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Table 3 Summary of the means ± SDs and percentages of correctly classified subjects in risk categories with regard to the TC, TG and D-LDL-C concentrations given by NCEP ATP III in the validation group

From: Evaluation of different formulas for LDL-C calculation

      

% of subjects properly classified by the following formulas

TC, mmol/L

n

D-LDL-C, mmol/L

F-LDL-C, mmol/L

A-LDL-C, mmol/L

S-LDL-C, mmol/L

Friedewald

Anandaraja

Modified

≤4.13

55

2.34 ± 0.44

2.13 ± 0.45**

2.12 ± 0.45**

2.28 ± 0.39

82%

84%

86%

4.14-5.16

192

3.1 ± 0.46

2.86 ± 0.43**

2.89 ± 0.41**

3.04 ± 0.39*

59%

52%

75%

5.17-6.20

310

3.88 ± 0.48

3.60 ± 0.41**

3.73 ± 0.43**

3.80 ± 0.38**

54%

42%

64%

6.21-7.24

287

4.78 ± 0.59

4.46 ± 0.43**

4.54 ± 0.42**

4.69 ± 0.39**

52%

47%

63%

≥7.25

199

5.92 ± 0.85

5.68 ± 0.77**

5.71 ± 0.70**

5.92 ± 0.77

92%

87%

94%

TG, mmol/L

        

≤1.13

280

3.83 ± 0.99

3.76 ± 0.97**

4.05 ± 1.04**

3.86 ± 0.98*

74%

59%

80%

1.14-1.68

324

4.32 ± 1.14

4.08 ± 1.08**

4.16 ± 1.08**

4.24 ± 1.08**

63%

59%

70%

1.69-2.25

217

4.58 ± 1.22

4.21 ± 1.21**

4.16 ± 1.21**

4.45 ± 1.20**

59%

54%

73%

2.26-2.82

97

4.64 ± 1.32

4.24 ± 1.41**

4.15 ± 1.35**

4.54 ± 1.41

55%

49%

65%

2.83-4.52

125

4.52 ± 1.32

3.98 ± 1.30**

3.85 ± 1.24**

4.4 ± 1.29*

49%

52%

67%

LDL-C, mmol/L

        

≤2.59

64

2.21 ± 0.30

2.07 ± 0.44**

2.23 ± 0.61

2.27 ± 0.39

91%

77%

81%

2.6-3.35

181

3.03 ± 0.21

2.90 ± 0.37**

3.00 ± 0.50

3.07 ± 0.35

61%

55%

71%

3.36-4.12

262

3.77 ± 0.22

3.60 ± 0.45**

3.71 ± 0.57*

3.79 ± 0.44

61%

45%

69%

4.13-4.89

213

4.50 ± 0.23

4.15 ± 0.42**

4.25 ± 0.56**

4.37 ± 0.39**

52%

49%

63%

≥4.9

323

5.67 ± 0.74

5.29 ± 0.81**

5.28 ± 0.81**

5.23 ± 0.81**

67%

66%

80%

  1. * p < 0.05, ** p < 0.001
  2. LDL-C: low-density lipoprotein cholesterol, D-LDL-C: directly measured LDL-C, F-LDL-C: LDL-C calculated by Friedewald's formula, A-LDL-C: LDL-C calculated by Anandaraja's formula, S-LDL-C: LDL-C calculated by the new modified formula.