From: Evaluation of different formulas for LDL-C calculation
% of subjects properly classified by the following formulas | ||||||||
---|---|---|---|---|---|---|---|---|
TC, mmol/L | n | D-LDL-C, mmol/L | F-LDL-C, mmol/L | A-LDL-C, mmol/L | S-LDL-C, mmol/L | Friedewald | Anandaraja | Modified |
≤4.13 | 55 | 2.34 ± 0.44 | 2.13 ± 0.45** | 2.12 ± 0.45** | 2.28 ± 0.39 | 82% | 84% | 86% |
4.14-5.16 | 192 | 3.1 ± 0.46 | 2.86 ± 0.43** | 2.89 ± 0.41** | 3.04 ± 0.39* | 59% | 52% | 75% |
5.17-6.20 | 310 | 3.88 ± 0.48 | 3.60 ± 0.41** | 3.73 ± 0.43** | 3.80 ± 0.38** | 54% | 42% | 64% |
6.21-7.24 | 287 | 4.78 ± 0.59 | 4.46 ± 0.43** | 4.54 ± 0.42** | 4.69 ± 0.39** | 52% | 47% | 63% |
≥7.25 | 199 | 5.92 ± 0.85 | 5.68 ± 0.77** | 5.71 ± 0.70** | 5.92 ± 0.77 | 92% | 87% | 94% |
TG, mmol/L | ||||||||
≤1.13 | 280 | 3.83 ± 0.99 | 3.76 ± 0.97** | 4.05 ± 1.04** | 3.86 ± 0.98* | 74% | 59% | 80% |
1.14-1.68 | 324 | 4.32 ± 1.14 | 4.08 ± 1.08** | 4.16 ± 1.08** | 4.24 ± 1.08** | 63% | 59% | 70% |
1.69-2.25 | 217 | 4.58 ± 1.22 | 4.21 ± 1.21** | 4.16 ± 1.21** | 4.45 ± 1.20** | 59% | 54% | 73% |
2.26-2.82 | 97 | 4.64 ± 1.32 | 4.24 ± 1.41** | 4.15 ± 1.35** | 4.54 ± 1.41 | 55% | 49% | 65% |
2.83-4.52 | 125 | 4.52 ± 1.32 | 3.98 ± 1.30** | 3.85 ± 1.24** | 4.4 ± 1.29* | 49% | 52% | 67% |
LDL-C, mmol/L | ||||||||
≤2.59 | 64 | 2.21 ± 0.30 | 2.07 ± 0.44** | 2.23 ± 0.61 | 2.27 ± 0.39 | 91% | 77% | 81% |
2.6-3.35 | 181 | 3.03 ± 0.21 | 2.90 ± 0.37** | 3.00 ± 0.50 | 3.07 ± 0.35 | 61% | 55% | 71% |
3.36-4.12 | 262 | 3.77 ± 0.22 | 3.60 ± 0.45** | 3.71 ± 0.57* | 3.79 ± 0.44 | 61% | 45% | 69% |
4.13-4.89 | 213 | 4.50 ± 0.23 | 4.15 ± 0.42** | 4.25 ± 0.56** | 4.37 ± 0.39** | 52% | 49% | 63% |
≥4.9 | 323 | 5.67 ± 0.74 | 5.29 ± 0.81** | 5.28 ± 0.81** | 5.23 ± 0.81** | 67% | 66% | 80% |