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Table 3 Summary of the means ± SDs and percentages of correctly classified subjects in risk categories with regard to the TC, TG and D-LDL-C concentrations given by NCEP ATP III in the validation group

From: Evaluation of different formulas for LDL-C calculation

       % of subjects properly classified by the following formulas
TC, mmol/L n D-LDL-C, mmol/L F-LDL-C, mmol/L A-LDL-C, mmol/L S-LDL-C, mmol/L Friedewald Anandaraja Modified
≤4.13 55 2.34 ± 0.44 2.13 ± 0.45** 2.12 ± 0.45** 2.28 ± 0.39 82% 84% 86%
4.14-5.16 192 3.1 ± 0.46 2.86 ± 0.43** 2.89 ± 0.41** 3.04 ± 0.39* 59% 52% 75%
5.17-6.20 310 3.88 ± 0.48 3.60 ± 0.41** 3.73 ± 0.43** 3.80 ± 0.38** 54% 42% 64%
6.21-7.24 287 4.78 ± 0.59 4.46 ± 0.43** 4.54 ± 0.42** 4.69 ± 0.39** 52% 47% 63%
≥7.25 199 5.92 ± 0.85 5.68 ± 0.77** 5.71 ± 0.70** 5.92 ± 0.77 92% 87% 94%
TG, mmol/L         
≤1.13 280 3.83 ± 0.99 3.76 ± 0.97** 4.05 ± 1.04** 3.86 ± 0.98* 74% 59% 80%
1.14-1.68 324 4.32 ± 1.14 4.08 ± 1.08** 4.16 ± 1.08** 4.24 ± 1.08** 63% 59% 70%
1.69-2.25 217 4.58 ± 1.22 4.21 ± 1.21** 4.16 ± 1.21** 4.45 ± 1.20** 59% 54% 73%
2.26-2.82 97 4.64 ± 1.32 4.24 ± 1.41** 4.15 ± 1.35** 4.54 ± 1.41 55% 49% 65%
2.83-4.52 125 4.52 ± 1.32 3.98 ± 1.30** 3.85 ± 1.24** 4.4 ± 1.29* 49% 52% 67%
LDL-C, mmol/L         
≤2.59 64 2.21 ± 0.30 2.07 ± 0.44** 2.23 ± 0.61 2.27 ± 0.39 91% 77% 81%
2.6-3.35 181 3.03 ± 0.21 2.90 ± 0.37** 3.00 ± 0.50 3.07 ± 0.35 61% 55% 71%
3.36-4.12 262 3.77 ± 0.22 3.60 ± 0.45** 3.71 ± 0.57* 3.79 ± 0.44 61% 45% 69%
4.13-4.89 213 4.50 ± 0.23 4.15 ± 0.42** 4.25 ± 0.56** 4.37 ± 0.39** 52% 49% 63%
≥4.9 323 5.67 ± 0.74 5.29 ± 0.81** 5.28 ± 0.81** 5.23 ± 0.81** 67% 66% 80%
  1. * p < 0.05, ** p < 0.001
  2. LDL-C: low-density lipoprotein cholesterol, D-LDL-C: directly measured LDL-C, F-LDL-C: LDL-C calculated by Friedewald's formula, A-LDL-C: LDL-C calculated by Anandaraja's formula, S-LDL-C: LDL-C calculated by the new modified formula.