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Table 2 Cardiac lipid profiling in PD2 and PD60 rats - effects of hypoxia and recovery.

From: Cardiac and plasma lipid profiles in response to acute hypoxia in neonatal and young adult rats

Lipid Class - Fatty Acid

Baseline

2 h of Hypoxia

2 h Recovery From Hypoxia

PD2 Heart

   

PE - 14:0

18.12 ± 1.94

33.72 ± 3.22 b

25.15 ± 3.88

TAG - 20:5n3

23.40 ± 2.23

13.97 ± 1.50a

18.22 ± 2.15

DAG - 16:0

162.65 ± 14.40

181.48 ± 10.22

215.03 ± 13.13a

DAG - 18:0

73.10 ± 5.66

79.82 ± 4.74

94.55 ± 2.95a

PC - 18:2n6

910.23 ± 51.81

1016.28 ± 43.05

1137.85 ± 37.57b

PC - 20:4n6

3357.63 ± 241.70

3829.30 ± 187.24

4163.98 ± 91.42a

PE - 22:5n3

348.03 ± 31.18

376.00 ± 13.45

445.35 ± 21.60a

PS - 18:2n6

73.93 ± 3.22

84.22 ± 3.55a

88.72 ± 1.69b

PS - 20:4n6

249.07 ± 29.52

317.28 ± 15.47a

368.38 ± 5.09d

PS - dm16:0

29.67 ± 3.93

41.53 ± 3.45

45.65 ± 3.74a

PD60 Heart

   

FFA - 16:0

503.55 ± 32.46

715.00 ± 70.41a

539.00 ± 18.51

FFA - 16:1n7

12.15 ± 0.55

44.85 ± 7.77d

15.00 ± 1.07

FFA - 18:1n9

200.07 ± 15.70

420.65 ± 49.30d

281.20 ± 11.50

FFA - 18:3n3

15.47 ± 1.26

37.97 ± 3.96e

18.77 ± 1.39

FFA - 18:2n6

438.52 ± 39.99

710.65 ± 90.36a

546.32 ± 32.84

FFA (total)

2093.50 ± 153.14

3000.00 ± 303.04a

2375.00 ± 88.179

TAG - 20:4n6

148.50 ± 21.07

324.10 ± 51.47a

182.02 ± 43.99

TAG - 18:1n9

517.25 ± 241.95

2694.30 ± 902.49a

500.62 ± 96.65

TAG (total)

999.25 ± 360.61

3986.00 ± 1295.06a

962.25 ± 163.08

  1. Animals were exposed to hypoxia (8% O2) for 2 h or exposed to hypoxia for 2 h and allowed to recover in room air (21% O2) for an additional 2 h. Due to the size of the data set produced by the lipid profiling analyses, only significant changes (p < 0.05) are shown. Data are presented as mean ± SEM (nmol/g tissue). All comparisons were made versus Baseline as follows: a P < 0.05, b P < 0.02, c P < 0.01, d P < 0.005, and e P < 0.001. Lipid class abbreviations can be found in the legend of Table 1.