Cardiac and plasma lipid profiles in response to acute hypoxia in neonatal and young adult rats

Table 3 Plasma lipid profiling in PD2 and PD60 rats - effects of hypoxia and recovery.

Lipid Class - Fatty Acid	Baseline	2 h of Hypoxia	2 h Recovery From Hypoxia
PD2 Plasma
FFA - 16:0	173.62 ± 15.61	90.62 ± 5.42^e	146.32 ± 7.90
FFA - 18:1n9	80.02 ± 10.08	37.60 ± 2.89^d	66.52 ± 3.73
FFA - 18:2n6	104.57 ± 6.31	47.90 ± 5.80^e	91.22 ± 3.16
FFA (total)	689.25 ± 53.22	344.50 ± 26.29^e	614.75 ± 27.21
PD60 Plasma
FFA - 16:0	192.52 ± 10.04	350.65 ± 12.19^e	160.42 ± 14.72
FFA - 16:1n7	19.45 ± 1.24	50.07 ± 2.90^e	17.00 ± 2.24
FFA - 18:1n9	101.42 ± 5.50	211.85 ± 3.29^e	82.70 ± 8.92
FFA - 18:2n6	167.85 ± 3.99	363.10 ± 11.27^e	134.65 ± 18.16
FFA (total)	653.00 ± 27.42	1249.00 ± 46.82^e	538.00 ± 53.79
TAG - 20:4n6	76.10 ± 8.94	177.45 ± 24.25^d	128.22 ± 9.35^a
LPC - 20:4n6	54.57 ± 5.55	36.55 ± 5.81^a	34.35 ± 1.46^a

Animals were exposed to hypoxia (8% O₂) for 2 h or exposed to hypoxia for 2 h and allowed to recover in room air (21% O₂) for an additional 2 h. Due to the size of the data set produced by the lipid profiling analyses, only significant changes (p < 0.05) are shown. Data are presented as mean ± SEM (nmol/g plasma). All comparisons were made versus Baseline as follows: ^a P < 0.05, ^b P < 0.02, ^c P < 0.01, ^d P < 0.005, and ^e P < 0.001. N = 4 samples for each experimental group. Note: plasma from 2-3 PD2 rats was pooled to generate one sample. Lipid class abbreviations can be found in the legend of Table 1.

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