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Table 2 Two-way analysis of variance (ANOVA) results.

From: Pharmacogenetic interaction between dexamethasone and Cd36-deficient segment of spontaneously hypertensive rat chromosome 4 affects triacylglycerol and cholesterol distribution into lipoprotein fractions

Phenotype

STRAIN

DEX

STRAIN*DEX

Body weight (b.wt.)

0.11

0.0027

0.25

Liver, g/100 g b.wt.

0.08

0.0004

0.07

Heart, g/100 g b.wt.

0.09

0.0005

0.48

Kidney, g/100 g b.wt.

0.41

0.0007

0.24

Adrenals, mg/100 g b.wt.

0.37

0.15

0.71

EFP wt., g/100 g b.wt.

0.012

0.06

0.78

RFP wt., g/100 g b.wt.

0.07

0.0023

0.26

Testes wt., g/100 g b.wt.

0.0027

0.16

0.67

Glucose (0 min)

0.20

<0.0001

0.50

Glucose (30 min)

0.31

<0.0001

0.14

Glucose (60 min)

0.0015

<0.0001

0.0005

Glucose (120 min)

0.0043

0.0001

0.046

Glucose (180 min)

0.07

<0.0001

0.032

AUC OGTT (0-180 min)

0.010

<0.0001

0.0048

Glycerol

0.37

0.11

0.38

Triacylglycerol (TG)

   

Total TG

0.21

0.0034

0.74

Chylomicron TG

0.60

0.48

0.08

VLDL-TG

0.19

0.0026

0.99

LDL-TG

0.37

0.0002

0.017

HDL-TG

0.028

0.14

0.59

F1 (CM)

0.54

0.43

0.09

F2 (CM)

0.69

0.57

0.06

F3 (large VLDL)

0.44

0.62

0.13

F4 (large VLDL)

0.19

0.09

0.50

F5 (large VLDL)

0.15

0.0011

0.83

F6 (medium VLDL)

0.18

<0.0001

0.42

F7 (small VLDL)

0.28

<0.0001

0.11

F8 (large LDL)

0.32

0.0004

0.0014

F9 (medium LDL)

0.36

0.0002

0.0031

F10 (small LDL)

0.29

0.0002

0.013

F11 (very small LDL)

0.52

0.0003

0.11

F12 (very small LDL)

0.70

0.0060

0.45

F13 (very small LDL)

0.95

0.06

0.76

F14 (very large HDL)

0.99

0.33

0.60

F15 (very large HDL)

0.81

0.66

0.48

F16 (large HDL)

0.62

0.39

0.57

F17 (medium HDL)

0.021

0.44

0.81

F18 (small HDL)

0.0021

0.0023

0.46

F19 (very small HDL)

0.0023

0.10

0.93

F20 (very small HDL)

0.015

0.0051

0.74

Cholesterol (C)

   

Total C

0.26

0.28

0.0017

Chylomicron C

0.58

0.89

0.0091

VLDL-C

0.0018

0.0081

0.35

LDL-C

0.13

0.0002

0.0006

HDL-C

0.21

0.0036

0.0059

F1 (CM)

0.55

0.82

0.0013

F2 (CM)

0.32

0.97

0.06

F3 (large VLDL)

0.54

0.38

0.10

F4 (large VLDL)

0.028

0.75

0.69

F5 (large VLDL)

0.0026

0.016

0.40

F6 (medium VLDL)

0.0009

0.0005

0.08

F7 (small VLDL)

0.025

0.0017

0.045

F8 (large LDL)

0.06

<0.0001

0.0085

F9 (medium LDL)

0.030

<0.0001

0.0007

F10 (small LDL)

0.08

<0.0001

0.0059

F11 (very small LDL)

0.11

0.0001

0.032

F12 (very small LDL)

0.52

0.94

0.0038

F13 (very small LDL)

0.47

0.014

0.0009

F14 (very large HDL)

0.21

0.0050

0.0019

F15 (very large HDL)

0.20

0.0048

0.0056

F16 (large HDL)

0.22

0.0067

0.018

F17 (medium HDL)

0.15

0.089

0.015

F18 (small HDL)

0.30

0.0004

0.0096

F19 (very small HDL)

0.41

<0.0001

0.11

F20 (very small HDL)

0.87

<0.0001

0.024

Lipoprotein particle size

   

VLDL-TG

0.06

<0.0001

<0.0001

LDL-C

0.15

<0.0001

0.09

HDL-C

0.59

0.44

0.0038

  1. The significance levels of two-way ANOVA's STRAIN, DEX and STRAIN*DEX factor interactions are shown (significant p values in bold, non-significant in italics). For glucose tolerance test, the time in minutes after the oral glucose load is indicated in parentheses. b.wt....body weight; EFP...epididymal fat pad; RFP...retroperitoneal fat pad. AUC OGTT...area under the glycaemic curve of the oral glucose tolerance test.
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Lipids in Health and Disease

ISSN: 1476-511X