Table 1 Clinical characteristics and metabolic measurements in plasma and adipose tissue of the subjects participating in the study.

Males (n)

10

11

8

Age (years)

47 [8]

47 [20]

38 [9]

BMI (kg/m²)

33.4 [2.4] **

34.5 [2.7] **

23.8 [1.2]

Waist circumference (cm)

111.4 [7.7] **

113.1 [6.7] **

84.9 [4.4]

Plasma cholesterol (mg/dl)

171.8 [25.9]

194.1 [29.9]

166.7 [24.2]

Plasma triglyceride (mg/dl)

111.2 [54.7]

99.8 [34.7]

72.4 [28.2]

LDL cholesterol (mg/dl)

102.1 [19.6]

114.9 [26.4]

96.8 [14.6]

HDL cholesterol (mg/dl)

34.5 [5.8] *§

44.3 [10.3]

47.7 [10.6]

Plasma glucose (mg/dl)

132.7 [37.2] *§

87.9 [13.9]

87.2 [9.9]

Plasma insulin (mU/l)

14.3 [6.4]

15.6 [4.2]

6.4 [1.5]

Plasma leptin (ng/ml)

9.4 [4.2]§

24.9 [9.6]**

5.4 [2.3]

Adipose tissue leptin mRNA (AU)

2.62 [1.90] *

1.73 [1.82]

0.77 [0.38]

Adipose tissue LPL activity

(nmol fatty acids/g tissue)

105 [45] *§

231 [128]

251 [119]

Insulin sensitivity (M-value) (mg/kg/min)

4.55 [1.41] **

4.63 [1.48] **

8.13 [2.32]

FFA during hyperinsulinaemic clamp (μmol/l)

84.0 [50.8] *

73.0 [33.7] *

36.2 [7.4]