Table 1 Serum liver function tests, lipid and apolipoprotein levels in control subjects and patients with liver cirrhosis.
Variable | Control subjects | Patients | p |
|---|---|---|---|
Albumin; g/L | 41.5 (1.6) | 36.6 (9.1) | 0.005 |
Alanine aminotransferase; μkat/L | 0.31 (0.08) | 1.08 (0.70) | 0.041 |
Aspartate aminotransferase; μkat/L | 0.35 (0.06) | 1.57 (0.99) | 0.025 |
γ-glutamyl transferase; μkat/L | 0.39 (0.27) | 1.19 (1.06) | 0.141 |
Alkaline phosphatase; μkat/L | 0.79 (0.25) | 5.81 (4.11) | 0.026 |
Bilirubin; μmol/L | 12.8 (1.9) | 19.4 (16.1) | 0.410 |
Total peroxides: μmol/L | 93.2 (12.2) | 338.8 (133.2) | 0.003 |
Monocyte chemoattractant protein-1; ng/L | 41.1 (3.4) | 146.0 (54.9) | 0.003 |
Type III procollagen-N-peptide; μg/L | 2.2 (1.3) | 10.2 (3.3) | 0.001 |
Paraoxonase-1 activity; U/L | 362.9 (36.6) | 94.9 (11.0) | < 0.001 |
Paraoxonase-1 concentration; mg/L | 62.1 (25.5) | 189.3 (48.3) | 0.002 |
Cholesterol; mmol/L | 5.26 (1.29) | 4.24 (2.00) | 0.366 |
Free cholesterol; mmol/L | 1.37 (0.36) | 1.48 (0.76) | 0.795 |
Triglycerides; mmol/L | 1.26 (0.19) | 1.31 (0.54) | 0.843 |
Phospholipids; mmol/L | 1.38 (0.36) | 1.48 (0.76) | 0.795 |
HDL-cholesterol; mmol/L | 1.80 (0.50) | 1.19 (0.27) | 0.044 |
Apolipoprotein A-I; g/L | 1.41 (0.40) | 0.89 (0.27) | 0.050 |
Apolipoprotein A-II; g/L | 0.31 (0.11) | 0.22 (0.11) | 0.234 |
Apolipoprotein E; mg/L | 25.59 (5.37) | 39.20 (24.62) | 0.262 |