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Table 1 Expression changes in different cells after AC-1041 treatment.

From: Polyunsaturated fatty acids synergize with lipid droplet binding thalidomide analogs to induce oxidative stress in cancer cells

Code Acc. No. Gene product K562 HL60 U266 HT168 U87 HEPG2 MCF7
CCL2 NM_002982 Chemokine (C-C motif) ligand 2 0.31 0.35 0.37 n.d. 0.80 0.34 0.51
ATF3 NM_004024 Activating transcription factor 3 10.21 2.75 8.17 18.29 4.10 0.66 4.32
DDIT3 NM_004083 DNA-damage-inducible transcript 3 3.73 3.28 6.19 3.67 2.84 2.91 6.43
LCRF NM_153607 Luman/CREB3 rercruitment factor 4.19 10.02 2.02 12.49 2.38 2.45 n.d.
DNAJB1 NM_006145 DnaJ (Hsp40) homolog B1 10.14 3.23 4.15 10.41 5.93 5.67 2.09
HERPUD1 NM_014685 ER stress-inducible, ubiquitin-like 1 2.76 1.76 1.02 7.63 2.57 3.81 2.03
HSPH1 NM_006644 Heat shock 105kDa/110kDa protein 1 3.64 2.69 1.70 3.26 1.88 2.27 0.89
TP53 NM_000546 Tumor protein p53 2.37 7.62 1.07 1.31 1.01 1.05 4.02
ING3 NM_019071 Inhibitor of growth family, member 3 1.63 2.10 1.80 1.92 1.59 0.72 2.51
LATS2 NM_014572 LATS, large tumor suppressor, homolog 2 2.62 1.73 1.20 3.57 2.11 0.24 0.65
CCND1 NM_053056 Cyclin D1 0.46 1.13 1.00 0.85 1.19 2.12 1.12
DUSP1 NM_004417 Dual specificity phosphatase 1 3.77 1.30 5.29 0.94 1.66 0.94 1.62
DUSP8 NM_004420 Dual specificity phosphatase 8 9.23 5.81 7.94 1.01 2.68 1.91 1.80
DUSP10 NM_007207 Dual specificity phosphatase 10 2.86 2.22 2.05 0.81 1.30 1.21 3.35
SNX16 NM_022133 Sorting nexin 16 3.19 3.07 1.39 1.07 0.75 1.24 1.92
  1. Down-regulated gene expression values (<1.80-fold) are indicated by bold, underlined numbers, induced expression values (>1.80-fold) by bold and italics.