Figure 5
From: Suppressive actions of eicosapentaenoic acid on lipid droplet formation in 3T3-L1 adipocytes
Possible mechanism involved in FA-regulated LD formation in adipocytes. Both SFA (stearic acid) and n-3 PUFA (eicosapentaenoic acid) have similar magnitude of effects towards lipolysis controlled by LPL and HSL. In contrast to upregulation shown by SFA, n-3 PUFA decreased PPARγ level, which may be responsible for the reduction of D9D/SCD1 and Cidea expressions, leading to smaller LDs. The levels of GLUT4 and Perilipin A remain unchanged upon FA treatment.