From: Gene activation regresses atherosclerosis, promotes health, and enhances longevity
Upregulation | Â |
---|---|
   Receptors | LXRα, PPARγ SR-B1, LDLR, CD36 |
   Enzymes | CYPs, LCAT, PON1 |
   Transporters | ABCA1, ABCG1, Apo AI |
Change in risk factor | Â |
   Increase | Apo AI, HDL-C, HDL2-C |
   Decrease | LDL-C, cholesterol, triglycerides |
Improvement | cellular cholesterol efflux |
 | peak pulmonary oxygen uptake |
 | glucose - insulin homeostasis |
 | weight control |
 | psychological wellbeing |
Lowering | blood pressure |
Decrease | CHD, cardiovascular, cancer and total mortality |