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Table 1 Effects of regular aerobic physical activity1

From: Gene activation regresses atherosclerosis, promotes health, and enhances longevity

Upregulation

 

   Receptors

LXRα, PPARγ SR-B1, LDLR, CD36

   Enzymes

CYPs, LCAT, PON1

   Transporters

ABCA1, ABCG1, Apo AI

Change in risk factor

 

   Increase

Apo AI, HDL-C, HDL2-C

   Decrease

LDL-C, cholesterol, triglycerides

Improvement

cellular cholesterol efflux

 

peak pulmonary oxygen uptake

 

glucose - insulin homeostasis

 

weight control

 

psychological wellbeing

Lowering

blood pressure

Decrease

CHD, cardiovascular, cancer and total mortality

  1. 1 The list of abbreviations precedes the reference list.