Table 2 Antiathrogenic effects of HDL/apolipoprotein AI
From: Gene activation regresses atherosclerosis, promotes health, and enhances longevity
Efflux and reverse transport of cholesterol | |
|---|---|
Anti-inflammatory | |
| Â | - inhibition of the expression of vascular cell adhesion molecules |
| Â | - stimulation of endothelial NO production |
Antioxidative | Â |
| Â | - inhibition of oxidative modification of LDL |
Antithrombotic | Â |
| Â | - inhibition of platelet aggregation |
| Â | - fibrinolysis |
| Â | - increase of prostacyclin production |
Facilitation of endothelial cell function and repair | |
Inhibition of apoptosis of endothelial cells | |