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Table 1 Baseline patient characteristics

From: Ezetimibe/simvastatin vs simvastatin in coronary heart disease patients with or without diabetes

Demographics

EZ/Simva 10/20

(N = 93)

Simva 40

(N = 106)

Age, yrs mean (SD)

62.8 (7.9)

62.9 (7.1)

Females

42 (45%)

36 (34%)

Body mass index, kg/m2, mean (SD)

73.7 (11.6)

75.1 (12.7)

Current smokers

16 (17.2%)

21 (19.8%)

Hypertension

58 (62.4%)

56 (52.8%)

Diabetes

37 (39.8%)

50 (47.2%)

Laboratory values

mean (SD)

LDL-C (mmol/L)

3.27 (0.47)

3.29 (0.44)

TC (mmol/L)

5.18 (0.58)

5.18 (0.56)

HDL-C (mmol/L)

1.26 (0.30)

1.19 (0.26)

TC/HDL-C

4.31 (1.03)

4.54 (1.00)

Triglycerides (mmol/L)

1.45 (0.62)

1.52 (0.59)

AST (U/L)

19.8 (5.3)

20.6 (4.7)

ALT (U/L)

22.7 (9.5)

25.5 (9.7)

CK (U/L)

97.0 (44.1)

110.7 (46.2)

Prevalence of cardiovascular diseases, n (%)

Cerebrovascular disease

30 (32.3%)

30 (28.3%)

Peripheral vascular disease

32 (34.4%)

39 (36.8%)

Ischemic heart disease

40 (43.0%)

49 (46.2%)

  1. ALT = alanine aminotransferase; AST = aspartate aminotransferase; CK = creatine kinase;
  2. EZ = ezetimibe; HDL-C = high-density lipoprotein cholesterol; LDL-C = low-density lipoprotein cholesterol; Simva = simvastatin; TC = total cholesterol