Lipid ratios and appropriate cut off values for prediction of diabetes: a cohort of Iranian men and women

Table 2 Odds ratios of lipid measures for incident diabetes mellitus

		Age adjusted model		multivariate adjusted model
	SD mmol/l	Odds ratio (95%CI)	P value	Odds ratio (95%CI)	P value	H-L X²(P value)	aROC (95%CI)
men
TC	1.1	1.28(1.09-1.52)	0.002	1.11(0.93-1.33)	0.2	5.65(0.7)	0.81
HDL-C	0.2	0.86(0.72-1.02)	0.1	0.91(0.75-1.09)	0.3	5.05(0.7)	0.81
TG	0.6*	1.62(1.37-1.92)	<0.001	1.23(1.02-1.49)	0.03	5.53(0.7)	0.82
Non-HDL-C	1.1	1.34(1.13-1.58)	<0.001	1.14(0.95-1.37)	0.15	6.59(0.6)	0.81
TC/HDL-C	1.7	1.44(1.22-1.69)	<0.001	1.27(1.06-1.51)	0.007	2.97(0.9)	0.82
TG/HDL-C	0.7*	1.44(1.25-1.65)	<0.001	1.25(1.03-1.52)	0.02	6.11(0.6)	0.82
women
TC	1.2	1.15(0.98-1.32)	0.1	0.94(0.80-1.12)	0.52	5.52 (0.7)	0.81
HDL-C	0.3	0.66(0.56-0.76)	<0.001	0.75(0.64-0.89)	0.001	3.67(0.9)	0.82
TG	0.5*	1.74(1.50-2.01)	<0.001	1.36(1.13-1.58)	0.001	7.94(0.4)	0.82
Non-HDL-C	1.2	1.26(1.09-1.45)	0.003	1.01(0.86-1.19)	0.86	4.34(0.8)	0.81
TC/HDL-C	1.7	1.37(1.21-1.55)	<0.001	1.14(0.99-1.31)	0.07	5.66(0.7)	0.81
TG/HDL-C	0.7*	1.78(1.53-2.06)	<0.001	1.39(1.17-1.64)	<0.001	7.47(0.5)	0.82

TC: total cholesterol, HDL-C: high density lipoprotein cholesterol, TG: triglycerides, SD: standard deviation, CI: confidence interval. aROC: area under the receiver operating characteristic of each model. Odd ratios indicate the increase risk for a 1 SD increase of each lipid parameter Multivariate models were adjusted for hypertension, family history of diabetes, general obesity and impaired glucose tolerance in men and for age, family history of diabetes, general obesity, abdominal obesity and impaired glucose tolerance in women. H-L X² indicates Hosmer and Lemeshow goodness of fit test. * SD of log-transformed.

ISSN: 1476-511X