Figure 3
From: Cardiac and vascular changes in elderly atherosclerotic mice: the influence of gender
Typical photomicrographs of aortic valves on a longitudinal axis from a male aged hypercholesterolemic ApoE KO and a normocholesterolemic C57 mouse. Samples were stained with hematoxylin-eosin (HE), Masson's trichrome (MT), and von Kossa (VK). Black arrows indicate diffuse acellularity and myxoid thickening of the spongy layer (HE, MT and VK) in the ApoE KO mouse. Red arrows indicated valvular fibrosis with dense collagen (MT) mainly in the ApoE KO mouse. Magnification: 250×.