Figure 5
From: Cardiac and vascular changes in elderly atherosclerotic mice: the influence of gender
Top panel: typical photomicrographs of cross sections of ascending aorta showing an augmented vessel diameter in the hypercholesterolemic ApoE KO compared with the normocholesterolemic C57 mouse. The sections were stained with both oil-red-O and hematoxylin (magnification: 400×). Bottom panel: Bar graphs showing average vessel (white bars) and lumen (black bars) cross-sectional areas of C57 (n = 6) and ApoE KO (n = 6) mice. Values are mean ± SEM. Numbers in parentheses indicate a positive remodeling ratio (>1.05). *p < 0.05 compared with vessel area of C57 groups.