Polysaccharide from Fuzi (FPS) Prevents Hypercholesterolemia in Rats

Table 1 Summary of lipid profiles in rats fed a high cholesterol diet and treated with different concentrations of FPS.

	Control (n = 10)	HC group (n = 10)	FPS (224 mg/kg) (n = 10)	FPS (448 mg/kg) (n = 10)	FPS (869 mg/kg) (n = 10)	P-value^
Cholesterol (mmol/L)	1.33 ± 0.19	2.89 ± 0.48^†	2.20 ± 0.38^†‡	1.91 ± 0.46^‡	1.93 ± 0.37^‡	<0.001*
Triglyceride (mmol/L)	0.79 ± 0.21	0.85 ± 0.33	0.88 ± 0.38	0.76 ± 0.36	0.87 ± 0.35	0.942
LDL-C (mmol/L)	0.79 ± 0.07	1.97 ± 0.46^†	1.20 ± 0.15^†‡	1.13 ± 0.10^‡	1.27 ± 0.21^†‡	<0.001*
HDL-C (mmol/L)	1.11 ± 0.17	1.22 ± 0.27	1.19 ± 0.24	1.11 ± 0.26	1.15 ± 0.33	0.830

Data are presented as the mean ± standard deviation.
HC = high cholesterol; FPS = Polysaccharide from Fuzi; LDL = low-density lipoprotein; HDL = high-density lipoprotein.
^P-values are based on analysis of variance testing.
* Indicates an overall significant difference (P < 0.05).
^† Indicates a statistically significant difference between the highlighted treatment group and the control group (P < 0.05).
^‡Indicates a statistically significant difference between the highlighted treatment group and the HC group (P < 0.05).
Pair-wise multiple comparisons between groups were determined using Bonferroni's test with α = 0.007 adjustment.

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