mRNA levels | Control (n = 10) | HC group (n = 10) | FPS (n = 10) | P-value^ |
---|
HMG-CoA reductase | 1.29 ± 0.36 | 4.17 ± 1.83† | 0.73 ± 0.39‡ | <0.001* |
CYP7α-1 | 0.78 ± 0.43 | 0.74 ± 0.49 | 4.08 ± 1.58†‡ | <0.001* |
- Data are presented as the mean ± standard deviation.
- HC = high cholesterol; FPS = Polysaccharide from Fuzi;
- ^P-values are based on analysis of variance testing.
- * Indicates an overall significant difference (P < 0.05).
- † Indicates a statistically significant difference between the highlighted treatment group and the control group (P < 0.05).
- ‡Indicates a statistically significant difference between the highlighted treatment group and the HC group (P < 0.05).
- Pair-wise multiple comparisons between groups were determined using Bonferroni's test with α = 0.017 adjustment.