Table 2 Laboratory value associations with HDL-C and Triglycerides in sickle cell disease
HDL Cholesterol (mg/dL) | Triglycerides (mg/dL) | |||
|---|---|---|---|---|
r | p | r | p | |
Hemoglobin | ||||
S hemoglobin (%) | -0.311 | 0.002 | 0.286 | 0.005 |
Fetal hemoglobin (%) | -0.048 | 0.644 | -0.685 | 0.685 |
Hemolysis | ||||
RBC (× 106/cu mm) | 0.328 | <0.001 | -0.190 | 0.019 |
Hemoglobin (g/dL) | 0.292♣ | <0.001 | -0.202 | 0.013 |
Hematocrit (%) | 0.309 | <0.001 | -0.189 | 0.020 |
Mean Cell Volume (fL) | -0.273♣ | 0.006 | 0.126 | 0.125 |
Mean Cell Hemoglobin (pg) | -0.284♣ | 0.002 | 0.111 | 0.175 |
Reticulocyte Count (%) | -0.170♣ | 0.046 | 0.082 | 0.339 |
Leukocyte | ||||
Leukocyte Count (× 109/L) | -0.198♣ | 0.015 | 0.081 | 0.325 |
Neutrophil Count (× 109/L) | 0.017♣ | 0.838 | -0.154 | 0.061 |
Monocyte Count (× 109/L) | -0.234 | 0.004 | 0.139 | 0.089 |
Platelets | ||||
Platelet Count (× 109/L) | -0.228♣ | 0.005 | 0.233 | 0.004 |
Hemolysis plus Hepatic | ||||
Aspartate aminotransferase (U/L) | -0.235♣ | 0.004 | 0.207 | 0.011 |
Total bilirubin (mg/dL) | -0.298♣ | <0.001 | 0.165 | 0.044 |
Direct bilirubin (mg/dL) | -0.471 | <0.001 | 0.035 | 0.669 |
Indirect bilirubin (mg/dL) | -0.287 | <0.001 | 0.140 | 0.088 |
Iron Serum (mcg/dL) | -0.186 | 0.038 | 0.159 | 0.076 |
Lactate dehydrogenase (U/L) | -0.375 | <0.001 | 0.167 | 0.041 |
Hepatic | ||||
Alanine aminotransferase (U/L) | -0.172 | 0.035 | 0.075 | 0.364 |
Total protein (g/dL) | -0.021♣ | 0.793 | 0.274 | 0.001 |
Albumin (g/dL) | 0.102 | 0.213 | 0.142 | 0.083 |
Globulin (g/dL) | -0.124♣ | 0.129 | 0.133 | 0.104 |
Albumin/Globulin ratio | 0.033 | 0.689 | -0.033 | 0.684 |
Renal | ||||
Urea nitrogen (mg/dL) | 0.178 | 0.030 | 0.020 | 0.806 |
Creatinine (mg/dL) | 0.118 | 0.152 | 0.105 | 0.201 |
Lipid metabolism | ||||
Total Cholesterol (mg/dL) | 0.299♣ | <0.001 | 0.268 | 0.001 |
HDL Cholesterol (mg/dL) | ---- | ---- | -0.228 | 0.005 |
LDL Cholesterol (mg/dL) | -0.083♣ | 0.312 | 0.068 | 0.409 |
VLDL Cholesterol (mg/dL) | -0.242 | 0.003 | 0.998 | <0.001 |
Triglycerides (mg/dL) | -0.228 | 0.005 | ---- | ---- |
Inflammation | ||||
C-reactive protein (mg/L) | 0.048 | 0.563 | -0.031 | 0.714 |
Alpha 1 antitrypsin (mg/dL) | -0.327♣ | <0.001 | -0.074 | 0.378 |
Ferritin (ng/mL) | -0.032 | 0.699 | 0.102 | 0.220 |
Antistreptolysin O (UI/mL) | -0.079 | 0.339 | 0.157 | 0.058 |