Adverse events, n (%) | Treatment period 1 | Treatment period 2 | Treatment period 3 | Total (n = 6) |
---|---|---|---|---|
Pradigastat 20 mg (n = 6) | Pradigastat 40 mg (n = 6) | Pradigastat 10 mg (n = 4) | ||
Diarrhea | 4 (66.7) | 5 (83.3) | 3 (75.0) | 6 (100.0) |
Abdominal pain | 3 (50.0) | 2 (33.3) | 1 (25.0) | 4 (66.7) |
Nausea | 0 (0.0) | 2 (33.3) | 1 (25.0) | 2 (33.3) |
Flatulence | 2 (33.3) | 2 (33.3) | 3 (75.0) | 4 (66.7) |
Abdominal pain upper | 2 (33.3) | 2 (33.3) | 0 (0.0) | 2 (33.3) |
Fecal incontinence | 1 (16.7) | 0 (0.0) | 0 (0.0) | 1 (16.7) |
Abdominal distension | 1 (16.7) | 0 (0.0) | 0 (0.0) | 1 (16.7) |
Dizziness | 0 (0.0) | 1 (16.7) | 0 (0.0) | 1 (16.7) |
Insomnia | 1 (16.7) | 1 (16.7) | 0 (0.0) | 1 (16.7) |
Dyspepsia | 1 (16.7) | 0 (0.0) | 0 (0.0) | 1 (16.7) |
Influenza | 1 (16.7) | 1 (16.7) | 0 (0.0) | 2 (33.3) |