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Table 1 Demographic and clinical characteristics of study participants

From: Relationship between CYP17A1 genetic polymorphism and coronary artery disease in a Chinese Han population

  Total Men Women
CAD Control P value CAD Control P value CAD Control P value
Number(n) 490 507   278 263   212 244  
Age, mean (SD) 61.94 (9.97) 61.20 (10.07) 0.242 60.65 (11.11) 59.70 (11.32) 0.326 63.63 (7.95) 62.81 (8.23) 0.280
EH, n (%) 236 (48.2) 219 (43.2) 0.115 119 (42.8) 106 (40.3) 0.555 117 (55.2) 113 (46.3) 0.059
Diabetes, n (%) 102 (20.8) 40 (7.9) <0.001 55 (19.8) 23 (8.7) <0.001 47 (22.2) 17 (7.0) <0.001
Smoking, n (%) 63 (12.9) 50 (9.9) 0.136 60 (21.6) 49 (18.6) 0.392 3 (1.4) 1 (4) 0.519
Drinking, n (%) 55 (11.2) 43 (8.5) 0.146 54 (19.4) 43 (16.3) 0.371 1 (5) 0 0.994
BMI, mean (SD) 25.85 (3.41) 25.48 (3.26) 0.076 26.41 (3.35) 25.72 (3.37) 0.018 25.26 (3.39) 25.16 (3.10) 0.753
SBP, mean (SD) 138.74 (26.35) 135.49 (24.09) 0.045 136.44 (25.77) 134.82 (23.11) 0.448 141.84 (26.87) 136.20 (25.13) 0.024
DBP, mean (SD) 85.78 (18.10) 84.18 (15.66) 0.143 85.48 (18.42) 84.52 (15.94) 0.521 86.17 (17.71) 83.81 (15.38) 0.136
Glu, mean (SD) 6.28 (2.69) 5.55 (1.73) <0.001 6.21 (2.77) 5.62 (1.92) 0.004 6.37 (2.57) 5.48 (1.50) < 0.001
TG, mean (SD) 2.24 (2.13) 1.90 (1.48) 0.005 2.30 (2.10) 2.04 (1.57) 0.110 2.15 (2.17) 1.75 (1.37) 0.026
TC, mean (SD) 4.25 (1.16) 4.33 (1.02) 0.306 4.06 (0.99) 4.18 (1.04) 0.160 4.51 (1.30) 4.48 (0.97) 0.777
HDL, mean (SD) 1.08 (0.33) 1.13 (0.32) 0.013 1.01 (0.28) 1.05 (0.29) 0.148 1.16 (0.38) 1.22 (0.33) 0.104
LDL, mean (SD) 2.51 (0.94) 2.55 (0.86) 0.457 2.43 (0.91) 2.52 (0.89) 0.220 2.80 (2.46) 2.57 (0.82) 0.212
UA, mean (SD) 320.94 (94.17) 321.07 (82.94) 0.982 344.51 (91.79) 348.25 (75.07) 0.609 289.55 (88.13) 291.72 (81.14) 0.788
Cr, mean (SD) 77.79 (33.00) 72.21 (17.82) 0.001 84.09 (33.96) 79.15 (16.84) 0.033 69.39 (29.73) 64.71 (15.71) 0.045
BUN, mean (SD) 5.38 (1.96) 5.29 (1.86) 0.446 5.54 (1.68) 5.51 (1.68) 0.822 5.17 (2.27) 5.05 (2.01) 0.562
  1. Data are presented as mean ± SD or n (%). Continuous variables are expressed as mean ± SD. Categorical variables are expressed as percentages. MI, body mass index; BUN, blood urea nitrogen; Cr, creatinine; DBP, diastolic blood pressure; DM, diabetes mellitus; Glu, glucose; TG, triglyceride; TC, total cholesterol; HDL, high density lipoprotein; LDL, low density lipoprotein; EH, essential hypertension; SBP, systolic blood pressure; UA, uric acid.
  2. The P value of the continuous variables was calculated by the Independent t-test. The P value of the categorical variables was calculated by Fisher’s exact test.