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Table 3 Molecular interaction studies of F18 bioactive compound and standards with HMG-CoA reductase

From: Bioactivity guided fractionation and hypolipidemic property of a novel HMG-CoA reductase inhibitor from Ficus virens Ait

S. No. Compound name binding energy ΔG (kcal/mol) Residues involved
1 n-Octadecanyl-O-α-D-glucopyranosyl(6′ → 1″)-O-α-D-glucopyranoside. −5.58 ASN755, ASP765, LYS691, GLU559, GLY560, ALA525, ARG590
2 Pravastatin −6.25 SER684, LYS735, ARG590, ASP690, GLU560, ASN658