Table 4 Predicted ADME profiles for F18 bioactive compound and standard
Compound | Aqueous Solubility Intensity | Intestinal Absorption Intensity | BBB Intensity | PPB % of binding | CYP450 Value | Hepatotoxicity | A logp 98 | Hydrogen bond acceptor | Hydrogen bond donor |
|---|---|---|---|---|---|---|---|---|---|
F18 | 3 | 3 | 4 | 0 | 0 | 0 | 3.863 | 11 | 7 |
Atorvastatin | 2 | 2 | 4 | 1 | 1 | 1 | 4.701 | 7 | 4 |