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Table 4 Predicted ADME profiles for F18 bioactive compound and standard

From: Bioactivity guided fractionation and hypolipidemic property of a novel HMG-CoA reductase inhibitor from Ficus virens Ait

Compound Aqueous Solubility Intensity Intestinal Absorption Intensity BBB Intensity PPB % of binding CYP450 Value Hepatotoxicity A logp 98 Hydrogen bond acceptor Hydrogen bond donor
F18 3 3 4 0 0 0 3.863 11 7
Atorvastatin 2 2 4 1 1 1 4.701 7 4