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Figure 1 | Lipids in Health and Disease

Figure 1

From: Effect of testosterone deficiency on cholesterol metabolism in pigs fed a high-fat and high-cholesterol diet

Figure 1

Schematic representation of the experimental design. Sexually mature male miniature pigs (6–7 months old) were fed a standard diet without cholesterol for 7 weeks. At week 7, the pigs were either surgically castrated or given a sham operation. Moreover, testosterone replacement therapy was given on the day of castration. Beginning at week 8, intact male pigs (IM + HFC), castrated pigs (CM + HFC), and castrated male pigs with testosterone replacement (CM + HFC + T) were fed the same high-fat and high cholesterol (HFC) diet for another 12 weeks, after which they were euthanized.

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