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Figure 5 | Lipids in Health and Disease

Figure 5

From: Effect of testosterone deficiency on cholesterol metabolism in pigs fed a high-fat and high-cholesterol diet

Figure 5

Effects of castration and testosterone replacement on hepatic HMGCR (A), CYP7A1 (B) activities, LDLR concentrations (C), and serum PCSK9 levels (D) in pigs fed a high-fat and high-cholesterol diet. HMGCR, 3-hydroxy-3-methylgutaryl coenzyme A reductase; CYP7A1, cholesterol 7α-hydroxylase; PCSK9, proprotein convertase subtilisin/kexin type 9. Data are presented as mean ± SEM; n = 6 pigs per group. *P < 0.05, **P < 0.01. Significant differences compared to the CM + HFC group determined by ANOVA (Tukey’s test).

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Lipids in Health and Disease

ISSN: 1476-511X