PPARD +294C overrepresentation in general and long-lived population in China Bama longevity area and unique relationships between PPARD +294T/C polymorphism and serum lipid profiles

Table 1 Comparison of clinical characteristics and serum lipid profiles between LG and non-LG

Parameter	LG (n = 505)	Non-LG (n = 468)	t(χ²)	P
N (male/female)	127/378	212/256	43.445	0.000
Age (years)	93.29 ± 2.93	68.28 ± 4.66	41.967	0.000
Chest (cm)	79.38 ± 7.28	81.30 ± 7.21	−4.057	0.000
Waist (cm)	77.02 ± 9.52	75.73 ± 9.26	2.101	0.036
Hip (cm)	84.25 ± 6.62	87.06 ± 6.38	−6.588	0.927
BMI (kg/m²)	20.22 ± 3.43	20.94 ± 3.17	−3.401	0.001
SBP (mmHg)	166.23 ± 28.14	149.45 ± 25.31	9.792	0.000
DBP (mmHg)	89.21 ± 13.65	84.76 ± 12.28	5.342	0.000
TC (mM)	5.08 ± 1.01	4.91 ± 0.94	2.656	0.008
TG (mM)	0.97(0.49)	0.93(0.47)	1.878	0.006
HDL-C (mM)	1.58 ± 0.38	1.62 ± 0.37	−1.550	0.122
LDL-C (mM)	3.00 ± 0.86	2.82 ± 0.80	3.491	0.001
Dyslipidemia n(%)	240(47.52)	204(43.59)	1.516	0.218
Hypertension n(%)	425(84.16)	290(61.97)	61.396	0.000

LG, long-lived group; non-LG, non-long-lived group; BMI: body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol. The values of triglyceride were presented as median (interquartile range) due to non-Gaussian distribution. The difference between the two groups was determined by the Wilcoxon-Mann–Whitney test.

ISSN: 1476-511X