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Table 3 Impact of PPARD +294T/C genotype on lipid levels

From: PPARD +294C overrepresentation in general and long-lived population in China Bama longevity area and unique relationships between PPARD +294T/C polymorphism and serum lipid profiles

Subgroup

Genotype

n

TC (mmol/L)

TG (mmol/L)

HDL-C (mmol/L)

LDL-C (mmol/L)

LG, all

TT

261

5.05 ± 0.99

0.96(0.49)

1.58 ± 0.39

2.97 ± 0.83

 

TC

192

5.03 ± 1.01b

0.97(0.49)b

1.60 ± 0.36

2.97 ± 0.90b

 

CC

52

5.40 ± 1.06b

1.10(0.48)b

1.54 ± 0.35

3.31 ± 0.83ab

 

TC/CC

244

5.11 ± 1.03b

0.98(0.50)b

1.58 ± 0.36b

3.04 ± 0.89b

LG, male

TT

58

4.76 ± 1.04c

0.97(0.48)

1.52 ± 0.41

2.75 ± 0.95c

 

TC

56

4.73 ± 1.07c

0.89(0.36)c

1.53 ± 0.40

2.77 ± 0.92

 

CC

13

5.37 ± 1.00d

0.94(0.26)

1.64 ± 0.53

3.30 ± 0.61d

 

TC/CC

69

4.85 ± 1.08c

0.92(0.33)c

1.55 ± 0.43

2.87 ± 0.89

LG, female

TT

203

5.13 ± 0.96

0.96(0.50)

1.60 ± 0.39

3.03 ± 0.78

 

TC

136

5.15 ± 0.97d

1.02(0.64)d

1.62 ± 0.35

3.05 ± 0.88d

 

CC

39

5.41 ± 1.09

1.15(0.56)

1.51 ± 0.27d

3.32 ± 0.90

 

TC/CC

175

5.21 ± 1.00d

1.04(0.63)d

1.59 ± 0.33d

3.11 ± 0.89d

Non-LG, all

TT

212

5.04 ± 0.91

0.97(0.55)

1.61 ± 0.38

2.93 ± 0.80

 

TC

204

4.77 ± 0.93

0.91(0.43)

1.63 ± 0.38

2.71 ± 0.79

 

CC

52

4.92 ± 0.99a

0.88(0.53)a

1.64 ± 0.32

2.79 ± 0.82a

 

TC/CC

256

4.80 ± 0.95a

0.89(0.44)a

1.63 ± 0.37

2.72 ± 0.79a

Non-LG, male

TT

100

4.96 ± 0.95

0.95(0.75)

1.57 ± 0.37

2.87 ± 0.85

 

TC

88

4.65 ± 1.05

0.91(0.49)

1.58 ± 0.37

2.63 ± 0.87

 

CC

24

4.59 ± 0.80c

0.88(0.37)a

1.52 ± 0.24c

2.66 ± 0.72

 

TC/CC

112

4.64 ± 1.00ac

0.90(0.48)a

1.57 ± 0.35c

2.63 ± 0.84a

Non-LG, female

TT

112

5.11 ± 0.88

1.00(0.41)

1.65 ± 0.38

2.99 ± 0.76

 

TC

116

4.86 ± 0.82

0.91(0.35)

1.66 ± 0.39

2.77 ± 0.72

 

CC

28

5.21 ± 1.07

0.87(0.61)

1.74 ± 0.35

2.90 ± 0.90

 

TC/CC

144

4.93 ± 0.88

0.89(0.43)a

1.68 ± 0.38

2.80 ± 0.75a

  1. aP < 0.05 in comparison with TT genotype of the same group; bP < 0.05 in comparison with the same genotype between LG and non-LG; cP < 0.05 intra-group comparison with the same genotype between sexes; dP < 0.05 intergroup comparison with the same genotype in males or females.