A coronary artery disease-associated SNP rs6903956 contributed to asymptomatic hyperuricemia susceptibility in Han Chinese

Table 3 The association of SNP rs6903956 genotype with aHU

Model	Genotype	Cases (n = 221)		Controls (n = 446)		OR (95% CI)^a	p ^a	Adjusted OR(95% CI)^b	p ^b
Model	Genotype	n	%	n	%	OR (95% CI)^a	p ^a	Adjusted OR(95% CI)^b	p ^b
codominant	GG	157	71.1	389	87.2	1.000 (Reference)		1.000 (Reference)
	GA	50	22.6	53	11.9	2.337(1.523-3.588)	<0.001	2.411(1.321-4.402)	0.004
	AA	14	6.3	4	0.9	8.672 (2.811-26.753)	<0.001	10.642(2.671-42.400)	0.001
dominant	GG	157	71.0	389	87.2	1.000 (Reference)		1.000 (Reference)
dominant	GA + AA	64	29.0	57	12.8	2.782(1.861-4.159)	<0.001	2.988(1.717-5.202)	<0.001
recessive	GG + GA	207	93.7	442	99.1	1.000 (Reference)		1.000 (Reference)
recessive	AA	14	6.3	4	0.9	7.473(2.430-22.983)	<0.001	9.205 (2.336-36.280)	0.002

^ausing univariate logistic regression analysis; ^badjusted for age, gender, BMI, smoking, hypertension, diabetes mellitus, abnormal glycometabolism, lipid abnormality, drinking. Odds ratio (95% confidence interval) was expressed for the risk of the other genotype when GG or GG+GA genotype was referenced.

ISSN: 1476-511X