Skip to main content

Table 2 Meta-analysis of the APOC3 rs5128 polymorphism and plasma APOC3 and lipids association

From: Associations of the APOC3 rs5128 polymorphism with plasma APOC3 and lipid levels: a meta-analysis

Groups or subgroups

Comparisons (n)

Q testPvalue

SMD (95% CI)

P

APOC3

    

All

18

0.004

0.22(0.12, 0.31)

<0.00001

All in HWE

15

0.007

0.20(0.09, 0.32)

0.001

Healthy

12

0.001

0.22(0.08, 0.35)

0.001

Male

5

0.135

0.11(−0.05, 0.27)

0.170

Caucasian

11

<0.00001

0.26(0.11, 0.40)

0.001

Asian

6

0.981

0.15(0.02, 0.29)

0.029

TG

    

All

64

<0.00001

0.33(0.23, 0.44)

<0.00001

All in HWE

48

<0.00001

0.31(0.20, 0.42)

<0.00001

Male

19

0.411

0.14(0.07, 0.21)

<0.00001

Female

8

0.062

0.17(0.04, 0.29)

0.011

Children

5

<0.00001

0.53(−0.37, 1.44)

0.249

Caucasian

38

<0.00001

0.39(0.24, 0.54)

<0.00001

Asian

17

0.302

0.18(0.12, 0.25)

< 0.00001

Other

9

< 0.00001

0.37(0.04, 0.69)

0.026

Healthy

39

< 0.00001

0.24(0.13, 0.35)

< 0.00001

CVD

9

0.188

0.29(0.16, 0.43)

< 0.00001

TC

    

All

49

< 0.00001

0.15(0.09, 0.22)

< 0.00001

All in HWE

41

0.06

0.12(0.07, 0.18)

< 0.00001

Male

13

0.52

0.06(−0.01, 0.14)

0.105

Female

6

0.23

0.20(0.07, 0.33)

0.002

Children

4

0.062

0.30(0.05, 0.55)

0.021

Caucasian

26

0.08

0.11(0.05, 0.18)

0.001

Asian

14

0.19

0.15(0.06, 0.24)

0.001

Other

9

< 0.00001

0.25(−0.03, 0.53)

0.081

Healthy

39

0.53

0.10(0.06, 0.14)

< 0.00001

CVD

7

0.46

0.15(0.04, 0.26)

0.008

Type 2 diabetes

4

0.18

0.24(0.05, 0.43)

0.013

LDL-C

    

All

42

< 0.00001

0.11(0.04, 0.17)

0.001

All in HWE

34

0.043

0.07(0.01, 0.13)

0.021

Male

11

0.069

0.06(−0.10, 0.12)

0.847

Female

6

0.197

0.13(0.02, 0.24)

0.021

Children

4

0.109

0.28(0.05, 0.51)

0.016

Caucasian

21

0.134

0.06(0.00, 0.13)

0.051

Asian

13

0.262

0.09(0.01, 0.16)

0.021

Other

8

< 0.00001

0.22(−0.06, 0.50)

0.119

Healthy

28

0.159

0.06(0.01, 0.11)

0.012

CVD

4

0.115

0.07(−0.13, 0.27)

0.482

Type 2 diabetes

4

0.996

0.22(0.08, 0.36)

0.002

HDL-C

    

All

54

0.314

−0.03(−0.06, 0.01)

0.156

All in HWE

42

0.195

−0.01(−0.06, 0.03)

0.597

Male

16

0.474

−0.01(−0.13, 0.00)

0.062

Female

7

0.663

−0.03(−0.11, 0.06)

0.540

Children

4

0.989

0.03(−0.13, 0.19)

0.733

Caucasian

30

0.763

−0.06(−0.10, −0.02)

0.007

Asian

16

0.173

0.06(−0.02, 0.13)

0.156

Other

8

0.562

−0.03(−0.06, 0.01)

0.536

Healthy

35

0.332

−0.03(−0.07, 0.011)

0.160

CVD

8

0.632

−0.02(−0.13, 0.09)

0.729

Type 2 diabetes

4

0.656

0.01(−0.14, 0.15)

0.915

  1. CVD: cardiovascular disease, TG: triglyceride, TC: total cholesterol, LDL-C: low-density lipoprotein cholesterol, HDL-C: high-density lipoprotein cholesterol.
Back to article page