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Table 3 Mean values x ¯ ± s of serum lipid and apolipoprotein levels for the Thr64 Arg site of the β3-AR gene in the overweight/obese and control groups

From: Effect of the beta-3 adrenergic receptor Trp64Arg and uncoupling protein 1–3826 A > G genotypes on lipid and apolipoprotein levels in overweight/obese and non-obese Chinese subjects

 

Overweight/obese

Controls

TrpTrp (n = 184)

Trp Arg + ArgArg (n = 65)

TrpTrp (n = 124)

TrpArg + ArgArg (n = 45)

TG (mmol/L)

2.40 ± 1.79

1.95 ± 1.11a,*

1.64 ± 1.05

2.05 ± 1.54

TC (mmol/L)

5.58 ± 1.02

5.33 ± 0.77

5.36 ± 1.04

5.77 ± 1.42b,*

HDL-C (mmol/L)

1.16 ± 0.31

1.24 ± 0.36

1.41 ± 0.41

1.44 ± 0.42

LDL-C (mmol/L)

d3.32 ± 0.91

e3.19 ± 0.73

f3.21 ± 1.01

g3.42 ± 1.15

apoA-I (mg/dL)

125.21 ± 29.49

124.33 ± 21.42

130.21 ± 22.58

126.13 ± 27.23

apoA-II (mg/dL)

28.54 ± 4.75

28.48 ± 4.90

28.53 ± 4.21

31.26 ± 11.61c,*

apoB100 (mg/dL)

93.44 ± 20.74

86.50 ± 14.41

89.38 ± 21.27

83.70 ± 23.98

apoC-II (mg/dL)

6.88 ± 3.50

6.12 ± 2.64

5.52 ± 2.95

5.99 ± 3.69

apoC-III (mg/dL)

15.92 ± 7.53

14.21 ± 4.79

13.04 ± 5.69

13.76 ± 7.67

Apo E (mg/dL)

5.39 ± 2.11

4.95 ± 1.42

4.75 ± 1.78

5.35 ± 3.29

  1. abcCompared with genotype TrpTrp carriers in the same group, respectively, *P < 0.05.
  2. Subjects with TG > 4.516 mmol/L (400 mg/dL) were excluded when calculating the serum LDL-C levels, d: n = 142, e: n = 51, f: n = 108, g: n = 37.
  3. Age and sex were used as covariates in the analysis to adjust for the genotype effects.