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Table 2 Plasma lipid and lipoprotein profiles in the entire cohort stratified by hepatic fat (%)

From: Amount of hepatic fat predicts cardiovascular risk independent of insulin resistance among Hispanic-American adolescents

Parameters, mean (SD) Hepatic fat < 5% Hepatic fat ≥ 5% and < 10% Hepatic fat ≥ 10% p-value
Standard lipid profile     
Cholesterol (mg/dl) 155 (21.8) 156 (31.6) 180 (50.9) 0.116
TG (mg/dl) 75.9 (26.7) 126 (71.8) 187 (117) 0.003
LDL (mg/dl) 98.5 (27.6) 102 (23.9) 117 (45.1) 0.247
HDL (mg/dl) 46.5 (8.48) 41.3 (7.75) 44.3 (9.45) 0.147
nonHDL (mg/dl) 109 (25.5) 115 (26.9) 136 (50.9) 0.113
TG/HDL ratio 1.76 (0.95) 3.16 (2.02) 4.23 (2.49) 0.006
apoB (mg/dl) 61.0 (17.9) 65.5 (16.2) 75.6 (28.7) 0.299
TG/apoB ratio 1.27 (0.37) 1.96 (0.94) 2.53 (1.65) 0.011
FFA (mEq/L) 0.81 (0.27) 0.80 (0.26) 1.15 (0.72) 0.071
Lipoprotein profile by NMR     
VLDL & Chy particles (nmol/L) 44.5 (21.6) 57.7 (24.0) 56.8 (31.0) 0.202
Large VLDL & Chy 1.32 (0.64) 5.01 (5.79) 6.46 (5.61) 0.019
Medium VLDL 13.9 (10.6) 23.9 (21.6) 25.1 (18.8) 0.202
Small VLDL 29.3 (14.5) 28.7 (13.1) 25.3 (12.4) 0.633
LDL particles (nmol/L) 864 (279) 945 (211) 1136 (481) 0.084
IDL 80.0 (42.8) 73.6 (66.2) 77.9 (64.1) 0.954
Large LDL 343 (121) 320 (188) 358 (165) 0.777
Small LDL 441 (295) 552 (267) 776 (445) 0.026
HDL particles (μmol/L) 31.1 (4.37) 30.0 (3.06) 31.7 (5.25) 0.409
Large HDL 5.69 (2.42) 4.20 (1.68) 4.11 (2.37) 0.043
Medium HDL 9.57 (9.57) 10.7 (4.25) 10.3 (4.23) 0.667
Small HDL 15.8 (3.28) 15.1 (4.79) 17.3 (5.04) 0.743
VLDL size (nm) 44.8 (4.73) 49.4 (8.12) 53.1 (7.94) 0.012
LDL size (nm) 20.7 (0.58) 20.6 (0.57) 20.5 (0.50) 0.664
HDL size (nm) 9.20 (0.45) 9.01 (0.32) 8.94 (0.41) 0.178
  1. P-values were generated using ANOVA or alternatively Kruskal-Wallis tests for variables with a non-normal distribution. Bold indicated statistical significance.