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Table 3 Relationship of the lipid and lipoprotein profiles with hepatic fat (%) as a continuous variable

From: Amount of hepatic fat predicts cardiovascular risk independent of insulin resistance among Hispanic-American adolescents

Variable Model 1 Model 2
Standard Lipid Profile   
Cholesterol (mg/dl) 0.006 (−0.005 – 0.017) 0.007 (−0.008 – 0.022)
TG (mg/dl) 0.053 (0.028 – 0.079)** 0.043 (0.006 – 0.081)*
LDL (mg/dl) 0.004 (−0.011 – 0.020) 0.013 (−0.010 – 0.035)
HDL (mg/dl) 0.001 (−0.009 – 0.010) −0.004 (−0.017 – 0.010)
nonHDL (mg/dl) 0.007 (−0.008 – 0.021) 0.010 (−0.011 – 0.031)
TG/HDL ratio 0.052 (0.025 – 0.080)** 0.047 (0.002 – 0.092)*
TG/apoB ratio 0.046 (0.025 – 0.067)** 0.032 (0.001 – 0.063)*
apoB (mg/dl) 0.007 (−0.008 – 0.023) 0.012 (−0.011 – 0.034)
Lipoprotein Compositions   
VLDL&Chy particles (nmol/L) 0.007 (−0.017 – 0.031) 0.006 (−0.031 – 0.043)
Large VLDL & Chy 0.069 (0.022 – 0.116)* 0.077 (0.011 – 0.043)*
LDL particles (nmol/L) 0.010 (−0.007 – 0.026) 0.015 (−0.010 – 0.040)
Small LDL 0.045 (0.007 – 0.083)* 0.059 (0.003 – 0.121)*
HDL particles (μmol/L) 0.002 (−0.005 – 0.009) 0.003 (−0.007 – 0.014)
Large HDL −0.013 (−0.037 – 0.011) −0.021 (−0.059 – 0.016)
VLDL size (nm) 0.008 (0.001 – 0.155)* 0.016 (0.002 – 0.022)*
LDL size (nm) −0.001 (−0.002 – 0.001) −0.001 (−0.003 – 0.001)
HDL size (nm) −0.001 (−0.003 – 0.001) −0.002 (−0.005 – 0.001)
  1. Model 1: Unadjusted.
  2. Model 2: adjusted for gender, BMI z-score, ALT, visceral fat, insulin, and insulin sensitivity.
  3. Data are expressed as β coefficient of change per one-unit change in % hepatic fat (95% confidence interval). ** p < 0.001; *p < 0.05; Data were log2 transformed. Bold indicated statistical significance.