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Figure 6 | Lipids in Health and Disease

Figure 6

From: Mechanism of the effect of glycosyltransferase GLT8D2 on fatty liver

Figure 6

The effect of GLT8D2 abnormality on the expressions of lipid synthesis and metabolism-related molecules (SREBP-1c, SCD, MTP and CPT-1). (A) Enhanced GLT8D2 decreased MTP expression in HepG2 cells with or without OA. Enhanced GLT8D2 has not obvious affect on the SREBP-1c, SCD and CPT-1 expressions in HepG2 cells with or without OA. (B) Inhibitory GLT8D2 increased MTP expression in HepG2 cells with or without OA. Inhibitory GLT8D2 has not obvious affect on the SREBP-1c, SCD and CPT-1 expressions in HepG2 cells with or without OA. Data are expressed as mean ± SD (n = 6); * p < 0.05 compared with cells with normal GLT8D2, respectively. White square without GLT8D2 and without OA. Light gray square with GLT8D2 and without OA. Dark gray square without GLT8D2 and with OA. Black square with GLT8D2 and with OA.

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