Table 2 Association of two SNPs in TRIB1 with CHD cases and controls in the Chinese Han populations
Genotypes | Cases n(%) | Controls n(%) | Crude OR (95%CI) | P-value | Adjusted ORa (95%CI) | P-value |
|---|---|---|---|---|---|---|
rs3201475 C > T | ||||||
CC | 212 (70.67) | 202 (67.33) | 1.00 (referent) | 1.00 (referent) | ||
CT | 83 (27.67) | 86 (28.67) | 1.09 (0.76–1.56) | 0.65 | 0.91 (0.54–1.54) | 0.72 |
TT | 5 (1.67) | 12 (4.00) | 2.52 (0.87–7.28) | 0.09 | 2.00 (0.48–8.25) | 0.34 |
rs17321515 G > A | ||||||
GG | 429 (32.2) | 936 (33.3) | 1.00 (referent) | 1.00 (referent) | ||
GA | 638(47.9) | 1388(49.4) | 1.00(0.86–1.16) | 0.97 | 1.00 (0.77–1.29) | 0.99 |
AA | 265(19.9) | 487 (17.3) | 1.19 (0.99–1.45) | 0.06 | 1.58 (1.13–2.20) | 0.01 |