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Table 3 Stratification analysis for association between SNP rs17321515 genotypes and risk of CHD

From: Association study of genetic variants at newly identified lipid gene TRIB1 with coronary heart disease in Chinese Han population

  

OR (95 % CI)a

P a

GG

GA

AA

Gender

Male

1.00

1.03(0.86–1.23)

1.28(1.01–1.61)

0.03

 

Female

1.00

0.94(0.69–1.27)

1.02(0.69–1.51)

0.86

Age(years)

≤60

1.00

1.22(0.96–1.55)

1.29(0.95–1.76)

0.11

>60

1.00

0.86(0.70–1.06)

1.15(0.88–1.49)

0.16

BMI(kg/m2)

<25

1.00

0.89(0.72–1.09)

1.20(0.93–1.54)

0.15

≥25

1.00

1.19(0.93–1.53)

1.21(0.87–1.68)

0.16

Smoke status

Non-smokers

1.00

0.96(0.75–1.21)

0.96(0.71–1.32)

0.82

Smokers

1.00

1.03(0.84–1.26)

1.41(1.09–1.88)

0.01

<20 cigarettes/day

1.00

0.97(0.72–1.30)

1.02(0.69–1.51)

0.95

≥20 cigarettes/day

1.00

1.06(0.84–1.33)

1.53(1.17–2.01)

0.002

Alcohol consumption

Non-drinkers

1.00

1.03(0.83–1.28)

1.25(0.95–1.65)

0.24

Drinkers

1.00

1.03(0.72–1.47)

1.16(0.73–1.83)

0.82

Diabetes

Yes

1.00

1.10(0.81–1.50)

1.32(0.90–1.94)

0.37

No

1.00

0.96(0.77–1.20)

1.03(0.77–1.38)

0.84

Hypertension

Yes

1.00

1.03(0.80–1.34)

1.18(0.84–1.64)

0.62

No

1.00

0.99(0.76–1.30)

1.20(0.85–1.69)

0.49

  1. a ORs and P values were obtained from a logistic regression model with adjustment for age, sex, smoking, BMI, blood pressure, blood glucose
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Lipids in Health and Disease

ISSN: 1476-511X