A review of the effect of omega-3 polyunsaturated fatty acids on blood triacylglycerol levels in normolipidemic and borderline hyperlipidemic individuals

Table 2 Alteration of serum TG levels in dietary intervention studies involving normolipidemic and moderately hyperlipidemic subjects

Study	N-3 PUFA Dose (g/d)	% Change in serum TG levels	Duration (wks)	Additional Dietary Modifications	Study	N-3 PUFA Dose (g/d)	% Change in serum TG levels	Duration (wks)	Additional Dietary Modifications
Normolipidemic Subjects – Modified EPA and/or DHA Intake					Moderately Hyperlipidemic Subjects – Modified EPA and/or DHA Intake
Lara [31]	5.4	−15*	4	Salmon Based	Ambring [33]
Dyerberg [27, 29]	4	−26*	8		Group A	4.1	−9*	4	Mediterranean Based
Hallund [32]					Group B	2.3	9	4	Swedish Based
Group A	3.4	−14	8	Trout Based	Sofi [42]
Group B	0.8	−6	8	Trout Based	Group A	2.3	−2	10	High LA diet
Navas-Carretero [34]	2.8	−3.1	8	Oily Fish Based	Group B	2.3	−2	10	Moderate LA diet
Minihane [41]					Group C	2.3	−12	10	Moderate LA diet
Group A	2	3	6	Moderate LA diet	Group D	2.3	−2	10	High LA diet
Group B	2	−5	6	High LA diet	Hamazaki [37]	0.86	−17*	12
Garcia-Alonso [36]	0.5	0	2
Baro [35]
Group A	0.33	2	8
Group B	0.33	1	4
Coates [38]	0.185	−27*	12
Normolipidemic Subjects – Modified ALA Intake					Moderately Hyperlipidemic Subjects – Modified ALA Intake
Stuglin [39]	6.98	41*	4	Ground Flaxseed	Dodin [28, 30]	8.53	3	52	Ground Flaxseed
Patenaude [40]					Dodin [28, 30]
Group A	6.5	−11	4	Ground Flaxseed
Group B	6.5	13	4	Ground Flaxseed
Group C	5.74	−20	4	Flaxseed Oil
Group D	5.74	4	4	Flaxseed Oil

*Asterisks denotes studies which found significantly different changes in serum TG levels (p < 0.05)

ISSN: 1476-511X