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Table 1 Fasting blood glucose and fasting insulin of control and experimental rats at baseline and after 28 days of treatment with Tetrapleura tetraptera hydroethanolic extract and metformin

From: Tetrapleura tetraptera spice attenuates high-carbohydrate, high-fat diet-induced obese and type 2 diabetic rats with metabolic syndrome features

Groups

Days

FBG (mmol/L)

Plasma insulin (μIU/mL)

NCD

0

5.28(4.61–5.94)bc

17.91(16.69–19.75)bc

28

5.39(4.83–5.55)bc

17.88(17.12–19.34)b

T28-T0

−0.23(−0.61–0.94)

−0.06(−0.78–0.43)

HCHFD

0

6.97(6.16–7.38)abc

40.3(38.95–45.91)a

28

7.03(6.11–7.44)abc

47.35(44.15–49.13) Sac

T28-T0

0.05(−0.05–0.11)

5.95(2.43–9.37)

HCHFD200

0

6.72(6.27–7.38)abc

39.79(37.23–45.32)a

28

5.44(4.66–6.16)Sbc

22.78(20.39–25.20)Sb

T28-T0

−1.48(−2.11_−0.72)

−17.4(−22.3_−13.03)

DBC

0

17.11(12.27–19)a

36.25(34.12–39.23)a

28

16.42(12.22–18.94)a

35.4(34.15–38.87)a

T28-T0

−0.31(−1.33–0.06)a

−0.26(−1.2–0.04)

DB200

0

16.55(12.44–18.33)Sabc

37(35.48–38.26)a

28

7.97(6.88–9.4)Sabc

24.74(22.31–27.01)Sabc

T28-T0

−8(−9.39_−5.56)

−11.75(−14.91_−9.76)

DB400

0

16.92(13.16–18.45)a

36.15(35.11–39.36)a

28

6.14(5.88_−7.05)Sbc

18.78(16.32–19.88)Sbc

T28-T0

−10.31(−12.57_−7.05)

−17.36(−23.04_−15.57)

DBMET

0

16.61(14.44–18.11)a

36.33(35.14–39.15)a

28

6.94(5.77–7.77)Sbc

20.62(19.22–23.15)Sbc

T28-T0

−9.59(−11_−6.83)

−16.15(−18.97−13)

  1. Ssignificant compared with T0 (p < 0.05). asignificant relative to normal control on the same treatment day(p < 0.05). bsignificant compared with HCHFD on the same treatment day. csignificant compared with diabetic control on the same treatment day (p < 0.05). (n = 6)