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Table 1 Fasting blood glucose and fasting insulin of control and experimental rats at baseline and after 28 days of treatment with Tetrapleura tetraptera hydroethanolic extract and metformin

From: Tetrapleura tetraptera spice attenuates high-carbohydrate, high-fat diet-induced obese and type 2 diabetic rats with metabolic syndrome features

Groups Days FBG (mmol/L) Plasma insulin (μIU/mL)
NCD 0 5.28(4.61–5.94)bc 17.91(16.69–19.75)bc
28 5.39(4.83–5.55)bc 17.88(17.12–19.34)b
T28-T0 −0.23(−0.61–0.94) −0.06(−0.78–0.43)
HCHFD 0 6.97(6.16–7.38)abc 40.3(38.95–45.91)a
28 7.03(6.11–7.44)abc 47.35(44.15–49.13) Sac
T28-T0 0.05(−0.05–0.11) 5.95(2.43–9.37)
HCHFD200 0 6.72(6.27–7.38)abc 39.79(37.23–45.32)a
28 5.44(4.66–6.16)Sbc 22.78(20.39–25.20)Sb
T28-T0 −1.48(−2.11_−0.72) −17.4(−22.3_−13.03)
DBC 0 17.11(12.27–19)a 36.25(34.12–39.23)a
28 16.42(12.22–18.94)a 35.4(34.15–38.87)a
T28-T0 −0.31(−1.33–0.06)a −0.26(−1.2–0.04)
DB200 0 16.55(12.44–18.33)Sabc 37(35.48–38.26)a
28 7.97(6.88–9.4)Sabc 24.74(22.31–27.01)Sabc
T28-T0 −8(−9.39_−5.56) −11.75(−14.91_−9.76)
DB400 0 16.92(13.16–18.45)a 36.15(35.11–39.36)a
28 6.14(5.88_−7.05)Sbc 18.78(16.32–19.88)Sbc
T28-T0 −10.31(−12.57_−7.05) −17.36(−23.04_−15.57)
DBMET 0 16.61(14.44–18.11)a 36.33(35.14–39.15)a
28 6.94(5.77–7.77)Sbc 20.62(19.22–23.15)Sbc
T28-T0 −9.59(−11_−6.83) −16.15(−18.97−13)
  1. Ssignificant compared with T0 (p < 0.05). asignificant relative to normal control on the same treatment day(p < 0.05). bsignificant compared with HCHFD on the same treatment day. csignificant compared with diabetic control on the same treatment day (p < 0.05). (n = 6)