Skip to main content

Table 8 Serum inflammatory markers, systolic blood pressure (SBP) and adiponectin in treated and untreated high-carbohydrate high-fat fed and type 2 diabetic rats

From: Tetrapleura tetraptera spice attenuates high-carbohydrate, high-fat diet-induced obese and type 2 diabetic rats with metabolic syndrome features

 

NCD

HCHFD

HCHFD200

DBC

DB200

DB400

DBMET

CRP (μg/mL)

194.5(168–224)bc

621(589–652)ac

330.5(310–369)20.77abc

728.5(697–769)ab

350(329–375)abc

129.5(119–153)abc

328(299–356)abc

IL-6 (pg/mL)

155(139–169)bc

240.5(230–251) a

182(175–192)abc

240(235–262)a

198.5(188–201)abc

150(143–160)bc

166(159–173)bc

TNF-α (μg/mL)

544.5(529–569)bc

851.5(816–873) a

657.5(643–670)abc

878(847–900)a

605(582–623)abc

543(516–560)bc

595(579–610)abc

Leptin (ng/mL)

3.2(2.9–3.8)bc

5.5(4.6–5.9) ac

3.93(3.66–4.36)abc

5.25(4.8–5.8)a

4.98(4.69–5.3)b

3.9(3.8–4.31)bc

3.12(2.7–3.26)bc

adiponectin (μg/mL)

45.85(42.9–47.1)bc

22.45(19.9–24.8) a

32.25(29.7–33.6)abc

25.5(24.1–28.4)a

24.5(21.6–26.9)a

32.1(28.6–32.9)abc

29.65(28.4–32.1)abc

SBP (mmHg)

91(87–96)3.51bc

147.5(142–153) a

113(110–117)abc

141(139–146)a

129.5(127–133)abc

108(101–112)abc

139.5(134–146)a

  1. asignificant relative to normal control (p < 0.05). bsignificant compared with HCHFD (p < 0.05). csignificant compared with diabetic control (p < 0.05). (n = 6)