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Table 8 Serum inflammatory markers, systolic blood pressure (SBP) and adiponectin in treated and untreated high-carbohydrate high-fat fed and type 2 diabetic rats

From: Tetrapleura tetraptera spice attenuates high-carbohydrate, high-fat diet-induced obese and type 2 diabetic rats with metabolic syndrome features

  NCD HCHFD HCHFD200 DBC DB200 DB400 DBMET
CRP (μg/mL) 194.5(168–224)bc 621(589–652)ac 330.5(310–369)20.77abc 728.5(697–769)ab 350(329–375)abc 129.5(119–153)abc 328(299–356)abc
IL-6 (pg/mL) 155(139–169)bc 240.5(230–251) a 182(175–192)abc 240(235–262)a 198.5(188–201)abc 150(143–160)bc 166(159–173)bc
TNF-α (μg/mL) 544.5(529–569)bc 851.5(816–873) a 657.5(643–670)abc 878(847–900)a 605(582–623)abc 543(516–560)bc 595(579–610)abc
Leptin (ng/mL) 3.2(2.9–3.8)bc 5.5(4.6–5.9) ac 3.93(3.66–4.36)abc 5.25(4.8–5.8)a 4.98(4.69–5.3)b 3.9(3.8–4.31)bc 3.12(2.7–3.26)bc
adiponectin (μg/mL) 45.85(42.9–47.1)bc 22.45(19.9–24.8) a 32.25(29.7–33.6)abc 25.5(24.1–28.4)a 24.5(21.6–26.9)a 32.1(28.6–32.9)abc 29.65(28.4–32.1)abc
SBP (mmHg) 91(87–96)3.51bc 147.5(142–153) a 113(110–117)abc 141(139–146)a 129.5(127–133)abc 108(101–112)abc 139.5(134–146)a
  1. asignificant relative to normal control (p < 0.05). bsignificant compared with HCHFD (p < 0.05). csignificant compared with diabetic control (p < 0.05). (n = 6)