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Table 1 Microarray data for candidate genes specifically up-regulated by nutrient overload

From: Fibrinogen production is enhanced in an in-vitro model of non-alcoholic fatty liver disease: an isolated risk factor for cardiovascular events?

Entrez gene ID

Accession

Gene Symbol

Description

Control

LPON

Control-LPON

OLE

Control-OLE

Max Mean value

Max Mean value

Direction of change wrt control

Maximum FC

RP pfp

Max Mean value

Direction of change wrt control

Max Mean value

RP pfp

2222

 

FDFT

farnesyl-diphosphate farnesyltransferase 1

1055.01

2501.65

↑

2.37121

0

1558.93

↑

1.47764

0.0194

2243

NP_000499

FGA

Fibrinogen alpha chain

3686.45

7280.47

↑

2.24956

0.0002

6716.9

↑

1.97551

0.0009

  1. FGA and FDFT were identified as candidate genes showing > 2.0 fold specific up-regulation of gene expression and protein abundance (see Table 2) in LPON-treated cells compared to untreated controls.
  2. LPON Lactate, pyruvate, octanoate and ammonia, FC fold change, RP pfp Rank products estimated percentage of false positive predictions; FGA Fibrinogen alpha chain, FDFT Farnesyl-diphosphate farnesyltransferase 1.