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Table 1 Microarray data for candidate genes specifically up-regulated by nutrient overload

From: Fibrinogen production is enhanced in an in-vitro model of non-alcoholic fatty liver disease: an isolated risk factor for cardiovascular events?

Entrez gene ID Accession Gene Symbol Description Control LPON Control-LPON OLE Control-OLE
Max Mean value Max Mean value Direction of change wrt control Maximum FC RP pfp Max Mean value Direction of change wrt control Max Mean value RP pfp
2222   FDFT farnesyl-diphosphate farnesyltransferase 1 1055.01 2501.65 2.37121 0 1558.93 1.47764 0.0194
2243 NP_000499 FGA Fibrinogen alpha chain 3686.45 7280.47 2.24956 0.0002 6716.9 1.97551 0.0009
  1. FGA and FDFT were identified as candidate genes showing > 2.0 fold specific up-regulation of gene expression and protein abundance (see Table 2) in LPON-treated cells compared to untreated controls.
  2. LPON Lactate, pyruvate, octanoate and ammonia, FC fold change, RP pfp Rank products estimated percentage of false positive predictions; FGA Fibrinogen alpha chain, FDFT Farnesyl-diphosphate farnesyltransferase 1.