Fibrinogen production is enhanced in an in-vitro model of non-alcoholic fatty liver disease: an isolated risk factor for cardiovascular events?

Table 3 Microarray data for predicted functional partners of FGA up-regulated by nutrient overload

Entrez gene ID	Accession	Gene symbol	Description	Control	LPON		Control-LPON		OLE		Control-OLE
Entrez gene ID	Accession	Gene symbol	Description	Maximum mean value	Maximum mean value	Direction of change wrt control	Maximum FC	RP pfp	Maximum mean value	Direction of change wrt control	Maximum FC	RP pfp
2266	NP_000500	FGG	Fibrinogen gamma chain	4612.12	1227.85	↑	2.10864	0.003	7458.56	↑	1.61716	0
2244	NP_001171670	FGB	Fibrinogen beta chain	644.648	1505.62	↑	2.33556	0.0018	1239.23	↑	1.92234	0.02
2267	NP_004458	FGL1	Fibrinogen-like 1	400.579	1086.52	↑	2.43005	0.003	884.484	↑	2.20802	0.0178
1471	NP_000090	CST3	Cystatin C	2153.68	5232.34	↑	2.42948	0	4730.95	↑	2.19668	0

>2 fold up-regulation in gene expression of FGG, FGB, FGL1 and CST3 were observed in LPON-treated cells compared to untreated controls.
For abbreviations: see Table 1.

ISSN: 1476-511X