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Table 1 General characteristics and serum lipid levels between the controls and patients

From: Association of polymorphisms in the MAFB gene and the risk of coronary artery disease and ischemic stroke: a case–control study

Characteristic

Controls (n = 539)

Patients

P

 

CAD (n = 525)

IS (n = 540)

P 1

P 2

P 3

Male/female

374/165

383/142

390/150

0.223

0.316

0.837

Age, years

63.08 ± 10.76

62.27 ± 10.93

62.81 ± 12.36

0.222

0.702

0.448

Body mass index, kg/m2

22.84 ± 3.51

23.29 ± 3.33

24.75 ± 5.18

0.033

0.048

0.135

Systolic blood pressure, mmHg

133.18 ± 22.95

137.00 ± 23.28

147.54 ± 21.98

0.007

<0.001

<0.001

Diastolic blood pressure, mmHg

79.78 ± 13.03

81.82 ± 14.13

83.71 ± 12.92

0.014

<0.001

0.023

Pulse pressure, mmHg

54.38 ± 17.94

55.86 ± 18.19

63.80 ± 17.98

0.185

<0.001

<0.001

Cigarette smoking, n (%)

220(40.8)

233(44.4)

226(41.9)

0.264

0.757

0.421

Alcohol consumption, n (%)

232(43.0)

220(41.9)

198(36.7)

0.710

0.035

0.090

Total cholesterol, mmol/L

4.70 ± 1.18

4.61 ± 1.18

4.52 ± 1.15

0.217

0.014

0.232

Triglyceride, mmol/L

1.08(0.81)

1.21(0.80)

1.36(0.93)

0.026

<0.001

<0.001

HDL-C, mmol/L

1.48 ± 0.49

1.45 ± 0.51

1.23 ± 0.40

0.267

<0.001

<0.001

LDL-C, mmol/L

2.78 ± 0.93

2.71 ± 0.90

2.68 ± 0.90

0.255

0.083

0.555

Apolipoprotein (Apo) AI, g/L

1.17 ± 0.32

1.15 ± 0.29

1.02 ± 0.22

0.200

<0.001

0.288

ApoB, g/L

0.89 ± 0.23

0.90 ± 0.25

0.89 ± 0.25

0.574

0.882

0.692

ApoAI/ApoB

1.45 ± 1.76

1.37 ± 0.66

1.17 ± 0.61

0.366

0.001

<0.001

Type 2 diabetes mellitus, n (%)

75(13.9)

117(22.3)

116(21.5)

<0.001

0.001

0.751

Hypertension, n (%)

174(32.3)

266(50.7)

289(53.5)

<0.001

<0.001

0.107

Hyperlipidemia, n (%)

198(36.7)

210(40.0)

212(39.3)

0.284

0.415

0.851

Using lipid-lowing drugs, n (%)

0(0)

172(32.8)

150(27.8)

<0.001

<0.001

0.077

  1. CAD coronary artery disease, IS ischemic stroke, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol
  2. P 1: comparison of CAD and controls; P 2: comparison of IS and controls; P 3: comparison of CAD and IS